Evidence map›Paper›PMID 41778196›Full record

ArticleFrontiers in physiology2026

Exploring the role of

Clarissa S G Da Fontoura, Steven Eliason, Brad A Amendt, Aline L Petrin, Lina M Moreno Uribe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Clarissa S G Da FontouraDepartment of Restorative Sciences, Cariology and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, United States.
Steven EliasonDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Brad A AmendtDepartment of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.
Aline L PetrinIowa Institute for Oral Health Research, College of Dentistry and Dental Clinics, University of Iowa, Iowa City, IA, United States.
Lina M Moreno UribeIowa Institute for Oral Health Research, College of Dentistry and Dental Clinics, University of Iowa, Iowa City, IA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Despite increasing evidence that common genetic variation contributes to variation in jaw and cranial base morphology, the biological mechanisms underlying malocclusion remain poorly defined. This study tested the hypothesis that a noncoding variant near Methods: In a cohort of 277 non-syndromic individuals with malocclusion, we performed targeted genotyping and deep sequencing of the Results: The SNP rs2189000, located 4.2 kb upstream of Conclusion: This study identifies a putative functional noncoding variant that dysregulates

Indexed as

geneticsgrowth and developmentmorphometricsorthodonticspolymorphisms

Identifiers

PMID41778196
PMCPMC12952720

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.