Evidence map›Paper›PMID 41777935›Full record

ArticleCureus2026

Effect of Preoperative Superselective Embolization in the Resection of Hypervascular Tumors of the Central Nervous System, Neck, and Nasal Cavity.

Luis Abraham Castro Toscano, Diego Julian Alvis Peña, Jorge Antonio Morales Baez, Heidy Margarita Castro Lopez, Karen Eloisa Xochipa Ruiz, Fernando de Jesus Espinosa Lira, Gustavo Melo Guzmán

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luis Abraham Castro ToscanoNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Diego Julian Alvis PeñaNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Jorge Antonio Morales BaezNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Heidy Margarita Castro LopezNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Karen Eloisa Xochipa RuizNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Fernando de Jesus Espinosa LiraNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.
Gustavo Melo GuzmánNeurosurgery and Neurological Endovascular Therapy, Juárez Hospital of México, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Hypervascular head and neck tumors, such as paragangliomas, esthesioneuroblastomas, and juvenile nasopharyngeal angiofibromas (JNA), are surgically challenging due to their rich vascular supply and proximity to critical structures. Preoperative superselective embolization may optimize surgical outcomes by reducing intraoperative bleeding and facilitating safe resections. Methods We conducted a retrospective case-control study of patients with hypervascular tumors of the central nervous system, neck, and nasal cavity treated between 2019 and 2024 at a single tertiary neurosurgical center. Patients were divided into embolization and non-embolization groups. Outcomes included the extent of resection, intraoperative blood loss, transfusion requirements, operative time, hospital stay, and complications. Results Fifty patients were analyzed (mean age 42.9 years; 58% female). Half underwent preoperative embolization, more frequently in nasal tumors (64%). Diagnoses included paraganglioma (46%), JNA (28%), and esthesioneuroblastoma (26%). Ethylene-vinyl alcohol copolymer was used in 96% of embolizations. Embolized patients had higher complete resection rates (100% vs. 84.6%; p<0.001), less blood loss (263.7 vs. 978.0 mL; p<0.001), fewer transfusions (16% vs. 84%; OR: 27.56), and shorter hospital stays (1.84 vs. 6.00 days; p<0.001). Complications were uncommon (8%) and transient. Conclusion Preoperative superselective embolization, particularly with ethylene-vinyl alcohol copolymer, is a safe and effective adjunct that improves resection rates, reduces perioperative morbidity, and optimizes surgical outcomes in hypervascular head and neck tumors.

Indexed as

esthesioneuroblastomahypervascular tumors of the central nervous systemjuvenile nasopharyngeal angiofibromasparagangliomaspreoperative embolization

Identifiers

PMID41777935
PMCPMC12951810

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.