Validation of the confusion assessment method for intensive care.

Objectives: Delirium is a common but frequently underdiagnosed complication in adult intensive care units (ICU), associated with increased morbidity, mortality, and healthcare costs. Early detection using validated tools is essential. This study aim to translate, adapt, and validate the Confusion Assessment Method for Intensive Care Units flowsheet (CAM-ICU flowsheet) into European Portuguese. Methods: A methodological, cross-sectional, descriptive-correlational study was conducted in a northern Portuguese ICU. The CAM-ICU flowsheet was translated and back-translated, followed by expert validation. Forty-two adult ICU patients on invasive mechanical ventilation were assessed using the adapted tool by two trained observers. Diagnostic accuracy was evaluated using DSM-5 criteria as the gold standard. Statistical analysis included sensitivity, specificity, kappa coefficient, and ROC curves. Results: Delirium was detected in 57.1 % of patients. The CAM-ICU flowsheet in European Portuguese demonstrated high interobserver agreement (κ=0.952), excellent sensitivity (100 %), and specificity (81.8-86.3 %). ROC AUC ranged from 0.909 to 0.932. The inattentiveness feature was the core for the presence or absence of delirium. Conclusions: The CAM-ICU flowsheet in European Portuguese was validated to assess delirium in nonverbal ICU patients on mechanical ventilation through this study and demonstrated to be a reliable and valid tool.