ReviewDental research journal2026
Effectiveness of silver diamine fluoride in preventing and arresting dental caries in pediatric dentistry.
Review in Dental research journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dental caries is one of the most prevalent chronic diseases among children worldwide. Conventional caries management methods such as fluoride sealants and varnishes are widely used; however, newer noninvasive therapies like silver diamine fluoride (SDF) have gained attention. SDF has been proposed as a topical treatment for pediatric carious lesions, with advantages including arresting caries progression, reducing pain, and promoting remineralization with minimal intervention. Materials and Methods: This review summarizes available evidence on the effectiveness of SDF as a caries prevention and arrest agent in primary teeth. It is based on a comprehensive analysis of current clinical studies and trials, focusing on biochemical mechanisms of action (including antimicrobial effects and increased dentin hardness), alongside practical considerations such as safety, application ease, and cost-effectiveness. Results: Across reviewed clinical studies and trials, SDF demonstrates effectiveness in preventing and arresting caries in primary teeth. Evidence supports underlying mechanisms including antimicrobial activity and enhancement of dentin hardness. The review also highlights practical strengths (safety profile, ease of application, and cost-effectiveness) and limitations, particularly esthetic concerns and staining. It also notes potential usefulness in pediatric populations with limited access to dental care or special healthcare needs. Conclusion: SDF can be applied safely, effectively, and cost-effectively as a caries-preventive and caries-arresting approach for young primary teeth.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.