ReviewDental research journal2026
Oral health-related quality of life in adults with cleft lip and/or palate: A systematic review.
Review in Dental research journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cleft lip and/or palate (CL/P) is a prevalent congenital craniofacial anomaly that affects facial esthetics, function, and psychosocial well-being. Oral health-related quality of life (OHRQoL) is a critical measure reflecting the impact of oral health on daily functioning and overall life quality. Despite extensive treatment, adults with CL/P may continue to face challenges affecting their OHRQoL. Objective: To systematically evaluate and synthesize the existing evidence on OHRQoL in adults (≥18 years) with CL/P. Materials and Methods: A systematic search was conducted across Scopus, Embase, Web of Science, and PubMed until March 2025. Eligible studies included those assessing OHRQoL in adults with CL/P, using validated questionnaires such as Oral Health Impact Profile-14 (OHIP-14) and Oral Impacts on Daily Performances. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed, and the protocol was registered in PROSPERO. Risk of bias was assessed using a modified Newcastle-Ottawa Scale for cross-sectional studies and the National Heart, Lung, and Blood Institute Quality Assessment Tool for pre-post studies. Due to heterogeneity in methodologies, a narrative synthesis approach was adopted. Results: From 407 identified records, 9 studies met the inclusion criteria. The majority were cross-sectional ( Conclusion: Despite receiving specialized, multidisciplinary treatment, adults with CL/P continue to experience impaired OHRQoL. These findings underscore the need for a more holistic, patient-centered care approach that includes psychological support and long-term follow-up. Future research should focus on longitudinal studies and explore strategies to address persistent psychosocial impacts in adulthood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.