Evidence map›Paper›PMID 41777713›Full record

ArticleChemical science2026

Microfluidic-mass spectrometry analysis of blood-brain barrier transport using engineered microparticle interfaces.

Shiyu Chen, Yingrui Zhang, Zengnan Wu, Tianze Xie, Tong Xu, Yi Zhang, Xianli Meng, Jin-Ming Lin

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiyu ChenSchool of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine Chengdu China.
Yingrui ZhangBeijing Key Laboratory of Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University Beijing 100084 China wzn@mail.tsinghua.edu.cn jmlin@mail.tsinghua.edu.cn.
Zengnan WuBeijing Key Laboratory of Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University Beijing 100084 China wzn@mail.tsinghua.edu.cn jmlin@mail.tsinghua.edu.cn.ORCID https://orcid.org/0000-0002-3766-2994
Tianze XieBeijing Key Laboratory of Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University Beijing 100084 China wzn@mail.tsinghua.edu.cn jmlin@mail.tsinghua.edu.cn.
Tong XuSchool of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine Chengdu 611137 China.ORCID https://orcid.org/0009-0001-7397-9585
Yi ZhangSchool of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine Chengdu 611137 China.
Xianli MengChinese Medicine Germplasm Resources Innovation and Effective Uses Key Laboratory of Sichuan Province, Institute of High Altitude Multimorbidity/TCM-Integrated High Altitude Medicine Center, Hospital of Chengdu University of Traditional Chinese Medicine Chengdu China xlm999@cdutcm.edu.cn.
Jin-Ming LinBeijing Key Laboratory of Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University Beijing 100084 China wzn@mail.tsinghua.edu.cn jmlin@mail.tsinghua.edu.cn.ORCID https://orcid.org/0000-0001-8891-0655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blood-brain barrier (BBB) is vital for maintaining central nervous system (CNS) homeostasis but represents a formidable obstacle to drug delivery, underscoring the need for physiologically relevant

Identifiers

PMID41777713
PMCPMC12951469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.