Evidence map›Paper›PMID 41777687›Full record

Trial reportPeerJ2026

Association between serum uric acid and urinary uric acid excretion indicators and early impaired kidney function in newly diagnosed T2DM patients with normal serum uric acid levels: a retrospective study.

Xinhang Li, Xiaodan Zhang

Abstract readClinical Trial
In one paragraph

Trial report in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xinhang Li *Department of Endocrinology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Xiaodan Zhang *Department of Endocrinology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To analyze the association between serum uric acid (SUA), urinary uric acid excretion indicators and early impaired kidney function (EIKF) in newly diagnosed type 2 diabetes (T2DM) patients with normal SUA levels, and to analyze their potential value in predicting the risk of EIKF. Methods: A cross-sectional study was conducted in 628 patients with newly diagnosed T2DM who were admitted to ward of endocrinology department. According to the renal function, patients were divided into non-EIKF group (estimated glomerular filtration rate (eGFR) ≥ 90 ml/min/1.73 m Results: Compared with non-EIKF group, patients in EIKF group were older and had a higher proportion of hypertension. Systolic blood pressure (SBP), HOMA-β, HOMA-IR, SUA, UACR, fractional excretion of uric acid (FEur), and estimated uric acid glomerular filtration (EurGF) levels were higher, while urinary uric acid (Uur), Conclusion: For newly diagnosed T2DM patients, even SUA levels are in the normal range, higher SUA, FEur and EurGF are associated with EIKF.

Indexed as

Diabetes Mellitus, Type 2Uric AcidAgedAlbuminuriaBiomarkersCreatinineCross-Sectional StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedRetrospective StudiesRisk FactorsROC CurveBiomarkersCreatinineUric AcidEarly impaired kidney functionType 2 diabetes mellitusUric acid

Identifiers

PMID41777687
PMCPMC12951882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.