Evidence map›Paper›PMID 41777678›Full record

ArticleInternational journal of general medicine2026

Latent Profile Analysis of Illness Perception and Its Association with Fear of Progression in Chronic Kidney Disease.

Lu Chen, Yue Wu, Jia-Hui Yang, Mei-Jing Zhou, Xiao-Lin Lv, Zheng Lin, Yan Cui

Abstract read
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Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Lu Chen *Department of Nursing, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Yue Wu *Department of Nursing, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Jia-Hui YangDepartment of Nephrology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Mei-Jing ZhouDepartment of Endocrinology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Xiao-Lin LvDepartment of Nephrology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Zheng LinDepartment of Nursing, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Yan CuiSchool of Nursing, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fear of progression (FoP) is one of the most prevalent psychological responses among patients with chronic kidney disease (CKD), impairing mental health and quality of life. However, research on the heterogeneity of illness perceptions among CKD patients remains limited, and the relationship between distinct perception profiles and FoP is not yet well understood. This study aimed to identify latent profiles of illness perception in CKD patients and examine their associations with FoP. Methods: In this cross-sectional study, a total of 428 CKD patients were recruited from four tertiary hospitals through convenience sampling between May 1, 2023, and April 30, 2024. Participants completed questionnaires assessing demographic and clinical characteristics, illness perception, FoP, psychological flexibility, family resilience, and social support. Latent profile analysis was conducted to identify illness perception profiles, multinomial logistic regression was used to examine predictors of profile membership, and stratified regression analyses were performed to assess the associations between illness perception profiles and FoP. Results: Latent profile analysis identified three distinct illness perception profiles. Multinomial logistic regression analysis indicated that CKD stage, number of concomitant symptoms, psychological flexibility, family resilience, and social support significantly predicted the latent profiles of illness perception (P < 0.05). Stratified regression analysis further demonstrated that illness perception profiles were independently predicted FoP after controlling for key demographic and clinical variables. Conclusion: CKD patients exhibit heterogeneity in illness perception. Illness perception profiles were associated with FoP. Distinct illness perception profiles are associated with FoP, and are influenced by key psychosocial factors. These findings support the development of tailored, perception-based interventions to reduce FoP among CKD patients.

Indexed as

chronic kidney diseasefear of progressionillness perceptionlatent profile analysis

Identifiers

PMID41777678
PMCPMC12950435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.