Evidence map›Paper›PMID 41777677›Full record

ArticleInternational journal of general medicine2026

Characterization of Gastric Mucinous Carcinoma: Clinicopathological Insights and Vascular Features via MSCT.

Yueqi Huang, Qingchun Li, Liujun Li, Mingqi Zhang, Yuchen Luo, Qian Shen, Shuai Xiao, Qiulin Huang

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Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yueqi Huang *Department of Ultrasound Medicine, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Qingchun Li *Radiological Imaging Center, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Liujun Li *Department of Ultrasound Medicine, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Mingqi ZhangDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Yuchen LuoDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Qian ShenDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.
Shuai XiaoDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.ORCID 0000-0003-0830-2188
Qiulin HuangDepartment of Gastrointestinal Surgery, the First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.ORCID 0000-0001-9212-0736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the clinicopathologic characteristics, Multi-slice Spiral CT (MSCT) vascular features, and angiogenesis profiles among mucinous gastric carcinoma (MGC), gastric carcinoma with <50% extracellular mucin pool (LEMPC), and non-mucinous gastric carcinoma (NMGC), and to explore imaging-angiogenesis associations underlying subtype-specific enhancement patterns. Patients and Methods: Clinical, radiological, and pathological data from patients with MGC, LEMPC, and NMGC were analyzed in a three-group comparative design. Microvessel density (MVD) and the expression of vascular endothelial growth factor A (VEGF-A), hypoxia-inducible factor-1 alpha (HIF-1α), and epidermal growth factor (EGF) were evaluated by immunohistochemistry in cancerous and corresponding paracancerous normal tissues. Correlations between MSCT features and histopathological parameters were assessed. Results: Overall survival was lower in the MGC group than in the NMGC group ( Conclusion: MGCs, marked by poor differentiation and poor prognosis, exhibit intact mucosal lines, frequent calcification, and stratified enhancement on enhanced MSCT. Reduced MSCT enhancement indices are associated with low angiogenesis, concomitant with decreased VEGF-A and EGF expression.

Indexed as

angiogenesisepidermal growth factorgastric mucinous carcinomahypoxia-inducible factor-1 alphamulti-slice spiral CTvascular endothelial growth factor A

Identifiers

PMID41777677
PMCPMC12951742

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