Evidence map›Paper›PMID 41777654›Full record

ArticleFrontiers in oncology2026

Case Report: pembrolizumab monotherapy achieves durable disease control in a patient with

Wei Zhao, Rong Zhou, Chunlai Feng

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei ZhaoDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Rong ZhouDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Chunlai FengDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the follow-up treatment options and prognosis in patient with non-small cell lung cancer (NSCLC) harboring a Case presentation: A patient with a 30-year smoking history and well-controlled hypertension developed lung adenocarcinoma (left upper lobe; T2aN2MO, Stage IIIA; Karnofsky Performance Status: 90) after radical lung cancer surgery. The patient was later hospitalized for "recurrent hemoptysis" and received pemetrexed adjuvant chemotherapy combined with cisplatin. The patient, subsequently developed focal brain metastasis for which he received radiotherapy. However, the patient experienced recurrent pulmonary lesions. The genetic testing and immunohistochemistry analysis revealed the presence of a Outcomes: The patient exhibited significant symptomatic improvement, with a marked reduction in recurrent and metastatic lesions. Subsequent follow-up assessments indicated stable disease with no evidence of progression. Moreover, only one low-grade immune-related adverse event was observed during the course of immunotherapy. Conclusion: Patients with advanced NSCLC and

Indexed as

BRAF V600E mutationcase reportimmune checkpoint inhibitornon-small cell lung cancerPD-L1

Identifiers

PMID41777654
PMCPMC12950602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.