Evidence map›Paper›PMID 41777588›Full record

ArticleBiology methods & protocols2026

Linking patient records at scale with a hybrid approach combining contrastive learning and deterministic rules.

Cheng Cao, Jay Pillai, Sara Daraei, Sina Ghadermarzi

Abstract read
In one paragraph

Article in Biology methods & protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cheng CaoTruveta Inc., 1745 114th Ave SE, Bellevue, WA 98004, United States.
Jay PillaiTruveta Inc., 1745 114th Ave SE, Bellevue, WA 98004, United States.
Sara DaraeiTruveta Inc., 1745 114th Ave SE, Bellevue, WA 98004, United States.
Sina GhadermarziTruveta Inc., 1745 114th Ave SE, Bellevue, WA 98004, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linking patient records across disparate healthcare systems is essential to create comprehensive views of patient health, yet this task is complicated by inconsistent identifiers and data quality issues. Although traditional deterministic and probabilistic record linkage (RL) methods have long been used for this purpose, deterministic approaches are brittle in the presence of noisy personally identifiable information (PII), while probabilistic approaches are often difficult to scale. As a result, large-scale linkage commonly relies on restrictive matching strategies that limit recall. This work presents a hybrid RL approach that integrates a deep embedding model with deterministic rules, leveraging both the flexibility and noise robustness of soft embeddings and the reliability and predictable baseline performance of deterministic rules. Using a large-scale real-world dataset, a BERT-based embedding model is fine-tuned in a Siamese network with contrastive loss to encode PII fields as numeric vectors. De-duplicated identifiers (Fuzzy IDs) are then obtained through a blocking-and-clustering step using the embedding vectors. The approach is evaluated using multiple signals (social security number, phone, and email) and is shown to outperform baseline methods. A postprocessing step based on deterministic rules allows embedding-based linkage to be overridden in a subset of cases where high-confidence rules apply, such as when a high-quality identifier is available. The system is deployed on a commercial database consisting of more than 200 million PII records, demonstrating scalability in a real-world healthcare setting.

Indexed as

contrastive learningdeterministic record linkageentity resolutionpatient matchingprobabilistic record linkage

Identifiers

PMID41777588
PMCPMC12952525

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.