Evidence map›Paper›PMID 41777586›Full record

ArticleJOR spine2026

Comparing Movement Patterns and Physical Function Between Chronic Low Back Pain Patients With Nociplastic and Nociceptive Pain Categories.

Erin Archibeck, Nicholas Harris, Patricia Zheng, Aaron Scheffler, Wolf Mehling, Conor O'Neill, Jeffrey Lotz, Grace O'Connell, Jeannie F Bailey, REACH Investigators

Abstract read
In one paragraph

Article in JOR spine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erin ArchibeckDepartment of Mechanical Engineering UC Berkeley Berkeley California USA.ORCID https://orcid.org/0009-0006-2852-975X
Nicholas HarrisDepartment of Orthopaedic Surgery UC San Francisco San Francisco California USA.
Patricia ZhengDepartment of Orthopaedic Surgery UC San Francisco San Francisco California USA.ORCID https://orcid.org/0000-0002-5855-5303
Aaron SchefflerDepartment of Epidemiology and Biostatistics UC San Francisco San Francisco California USA.
Wolf MehlingOsher Center for Integrative Health, UC San Francisco San Francisco California USA.
Conor O'NeillDepartment of Orthopaedic Surgery UC San Francisco San Francisco California USA.
Jeffrey LotzDepartment of Orthopaedic Surgery UC San Francisco San Francisco California USA.
Grace O'ConnellDepartment of Mechanical Engineering UC Berkeley Berkeley California USA.ORCID https://orcid.org/0000-0003-0746-1638
Jeannie F BaileyDepartment of Orthopaedic Surgery UC San Francisco San Francisco California USA.ORCID https://orcid.org/0000-0003-4618-7512
REACH Investigators

Funding

UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back PainU19AR076737 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUG, ROLAND · 2019 to 2023
$34.1M
Mechanistic structure-function relationships for paraspinal muscle fat infiltration in chronic low back pain patientsR01AR081324 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jeannie Fern Bailey · 2023 to 2026
$1.4M
NIAMS NIH HHS R01 AR081324NIAMS NIH HHS U19 AR076737
6 · The paper itself

Abstract

Background: Individuals with chronic low back pain (LBP) often present with significant physical dysfunction. The underlying cause is difficult to diagnose due to the heterogeneous nature of LBP categories. Methods: Two hundred and fifty-six patients were assessed as having either nociceptive (NC) or nociplastic (NP) chronic low back pain using validated surveys, including the PainDETECT Questionnaire and a chronic overlapping pain condition screener. Additional covariates of anxiety, depression, and fear avoidance were evaluated using standard surveys. Physical function was judged objectively using a sit-to-stand test (STS; quantified using marker-less motion capture calculated kinematic scores and movement metrics) and subjectively (PROMIS-physical function survey). Demographics (age, sex, BMI), psychological factors, and biomechanical outcomes were compared across pain categories using nonparametric statistics and regression modeling. Results: Compared to the NC group, the NP group was significantly older (NP: 61.0 ± 21.0, NC: 53.5 ± 29.3, Conclusion: While individuals with nociplastic pain reported lower perceived physical function and exhibited differences in demographic and psychological factors, pain categories were not significant predictors of objective biomechanical measures after adjusting for age, sex, and BMI. However, pain category was a significant predictor of PROMIS-PF, suggesting that it is more closely associated with perceived functional limitations than with quantitative biomechanical performance.

Indexed as

biomechanicschronic low back painpain categoriesphysical function

Identifiers

PMID41777586
PMCPMC12950820

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.