ReviewMaterials today. Bio2026
Microalgal therapeutic peptides: From biomass to bone tissue engineering.
Review in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone tissue engineering continues to face challenges in developing biomaterials that are both safe and biologically active, particularly in promoting integration with native tissue. Traditional synthetic materials often lack cellular compatibility, driving research toward natural and biomimetic alternatives. In this context, microalgae have a diverse metabolic profile, producing several biologically active compounds (i.e. lipids, carbohydrates, pigments) with therapeutic potential for bone regeneration. Among these, peptides gain relevance due to their high cellular compatibility, osteogenic activity and tunable properties. Herein, this review provides a comprehensive and critical overview of microalgae-derived peptides, covering their manufacturing process. It covers the entire workflow from protein extraction to peptide purification and characterization. It summarizes their biological properties and therapeutic applications in bone regeneration and examines their status in clinical studies alongside the main regulatory and translational challenges. Particular focus will be given to the combination of advanced delivery systems for using microalgae therapeutic peptides to develop patient-specific implants. Overall, this review emphasizes the significance of microalgae as a versatile and sustainable resource to extract therapeutic peptides and to develop the next generation of biomaterials in bone regenerative medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.