ArticleNational science review2026
Pavlov's experiment-inspired optical neural networks based on dual-color fluorescence switching effect.
Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cutting-edge optical neural networks are often still trained by backpropagation, which is computationally intensive and originally for conventional artificial neural networks. Inspired by Pavlov's experiment, we drew upon the principles of biological memory to establish an associative learning framework for training optical neural networks that mimics the mechanisms of associative learning and synaptic plasticity using dual-wavelength stimuli (i.e. ultraviolet and visible light) on a dual-color photoinitiator resin. Sequential light irradiation was shown to induce fluorescence switching and encode associative memory in the resin, which can serve as a physical substrate for an optical neural network. In optical experiments, the established framework was applied to pattern recognition of the letters 'N,' 'V,' and 'Z.' Simulations were conducted that extended its application to the recognition of handwritten digits. Compared to the current mainstream 'bottom-up' optical neural network fabrication approach that requires 'weight calculation followed by hardware implementation', this work presents a novel 'top-down'
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