Evidence map›Paper›PMID 41777496›Full record

ArticleNoro psikiyatri arsivi2026

Novel Genetic Insights into Lateral Temporal Lobe Epilepsy: Findings from Whole Exome Sequencing.

Barış Salman, Yeşim Kesim, Nermin Görkem Şirin, Seda Süsgün, Güneş Altıokka Uzun, Sibel Uğur İşeri, Nerses Bebek, Betül Baykan

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In one paragraph

Article in Noro psikiyatri arsivi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Barış SalmanIstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, Istanbul, Türkiye.
Yeşim KesimOxford NIHR Biomedical Research Centre, University of Oxford, UK.
Nermin Görkem ŞirinIstanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Türkiye.
Seda SüsgünIstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, Istanbul, Türkiye.
Güneş Altıokka UzunIstanbul University, Graduate School of Health Sciences, Istanbul, Türkiye.
Sibel Uğur İşeriIstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Genetics, Istanbul, Türkiye.
Nerses BebekIstanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Türkiye.
Betül BaykanIstanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lateral temporal lobe epilepsy (LTLE) is characterized by auditory auras and is often associated with genetic factors. Previous studies have identified various genes linked to LTLE, including Methods: A cohort followed in our epilepsy center and diagnosed as LTLE with auditory aura was recruited to the study. We have performed whole exome sequencing data analysis of 19 patients using a two-step approach. In the first step, we have focused on six LTLE associated genes, namely Results: Our analysis identified novel variants in LTLE-associated genes, including Conclusion: Our study underscores the genetic heterogeneity of lateral temporal lobe epilepsy (LTLE) by identifying new genetic variants linked to the disorder. Notably, we propose that

Indexed as

epilepsy with auditory featuresexome sequencingLateral temporal lobe epilepsyLGI1SCN1A

Identifiers

PMID41777496
PMCPMC12951495

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.