Evidence map›Paper›PMID 41777410›Full record

ArticleEcancermedicalscience2026

Oncology with common sense: beyond biologistic and pharmacological models.

Rodrigo Lastra, Patricia Iranzo, Javier-David Benítez-Fuentes, Ana Callejo, Mara Cruellas, Jacobo Gómez Ulla, Isabel Pimentel, José Luis Pérez-Gracia, Marta Ramos, Francisco Gil Moncayo and 12 more

Abstract read
In one paragraph

Article in Ecancermedicalscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Rodrigo LastraRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Patricia IranzoRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Javier-David Benítez-FuentesRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Ana CallejoRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Mara CruellasRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Jacobo Gómez UllaRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Isabel PimentelRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
José Luis Pérez-GraciaOncology Department, Hospital Universidad de Navarra, Av Pio XII, 36, 31008 Pamplona, Spain.
Marta RamosRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Francisco Gil MoncayoPsycho-Oncology Department (Head), Institut Catalad'Oncologia, Gran via de l'Hospitalet 199-203, 08908 L'Hospitalet de Llobregat (Barcelona), Spain.
María Álvarez AlejandroRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Marta GascónRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Sergio Martínez RecioRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Pilar RiveroOncology Department, Hospital de Barbastro, Avenida de la Constitucion, 22300 Barbastro (Huesca), Spain.
Jorge BartoloméOncology Department, Hospital Clinico San Carlos & Experimental Therapeutics in Cancer Unit, Instituto de Investigacion Sanitaria San Carlos (IdISSC), Calle del Profesor Martin Lagos, 28040 Madrid, Spain.
Antonio David Lázaro SánchezRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
David Fernández GarayOncology Department, Hospital Regional Universitario Málaga, Avenida de Carlos Haya, 29010 Málaga, Spain.
Alicia de Luna AguilarRio Working Group, C/Ram de Viu 35 B D, 50006 Zaragoza, Spain.
Isabel Lorenzo LorenzoOncology Department, Complejo Hospitalario Universitario de Vigo, Calle Ramon y Cajal, 36202 Vigo (Pontevedra), Spain.
Joan BrunetOncology Department, Institut Catala d'Oncologia, Avinguda França, 17007 Girona, Spain.
Noemi ReguartOncology Department, August Pi Sunyer Biomedical Research Institute (IDIBAPS), Carrer de Villarroel, 170 08036 Barcelona, Spain.
Dario TrapaniEuropean Institute of Oncology, IRCCS, Via Ripamonti, 435, 20141 Milano MI, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid advances in oncology have led to unprecedented pharmacological and technological complexity, yet these developments have not always translated into meaningful benefits for patients. Inspired by the Common Sense Oncology movement, this article reflects on the need to recalibrate cancer care beyond biologistic and industry-driven models. We argue for a broader, patient-centred vision of oncology that integrates social determinants of health, prevention, supportive and palliative care, shared decision-making and independent research alongside pharmacological innovation. Drawing on evidence from health economics, clinical research trends and public health, we highlight the paradox between rising oncology expenditures and limited gains in overall survival, quality of life and equity. We also discuss the growing influence of industry-sponsored research, the increasing reliance on surrogate endpoints, and the underfunding of non-pharmacological and psychosocial interventions. Finally, we propose concrete priorities for policymakers, clinicians and research institutions to ensure that oncology progress remains aligned with outcomes that truly matter to patients.

Indexed as

clinical and financial toxicitycommon sense oncologyhealth inequalitiespatient-centered caresocial determinants of healthvalue-based oncology

Identifiers

PMID41777410
PMCPMC12950886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.