Evidence map›Paper›PMID 41777338›Full record

ArticleEndoscopy international open2026

Second lesions located within the same belt-like region along the stomach's short axis as primary lesions: Boundary equal lesion trends.

Toshifumi Iida, Yoshiaki Kimoto, Etsuko Yamabe, Miuzen Kanamori, Susumu Banjoya, Tomoya Kimura, Koichi Furuta, Shinya Nagae, Hiroshi Yamazaki, Nao Takeuchi and 8 more

Abstract read
In one paragraph

Article in Endoscopy international open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Toshifumi IidaDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.ORCID 0009-0005-9694-4667
Yoshiaki KimotoDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.ORCID 0000-0003-4813-342X
Etsuko YamabeDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Miuzen KanamoriDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Susumu BanjoyaDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Tomoya KimuraDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Koichi FurutaDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Shinya NagaeGastroenterology, Itabashi Chuo Medical Center, Itabashi, Japan.
Hiroshi YamazakiDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Nao TakeuchiDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.ORCID 0000-0002-4508-8283
Shunya TakayanagiMedicine, Haukeland University Hospital, Bergen, Norway.
Takafumi KonishiDepartment of Gastroenterology, Rinku General Medical Center, Izumisano, Japan.
Yuki KanoDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Kohei OnoDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Ryoju NegishiItabashi Chuo Medical Center, Itabashi, Japan.
Yohei MinatoDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.
Hideyuki ChibaGastroenterology, Omori Red Cross Hospital, Ota-Ku, Japan.ORCID 0000-0001-9766-509X
Ken OhataDepartment of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Gastric adenoma and cancer are common in Asia, with early detection critical for prognosis. Synchronous multiple early gastric cancers (SMEGCs) occur in 6% to 14% of cases, but their clinicopathological characteristics remain unclear. This study analyzed synchronous multiple gastric neoplasms treated by endoscopic resection or surgery to aid early detection. Patients and methods: Among 2,991 cases of early gastric cancer or adenoma diagnosed at our institution, 173 patients with 346 synchronous lesions (January 2016-March 2024) were analyzed. All lesions were mucosal or submucosal. Lesions were categorized as "1st" (larger) and "2nd" (smaller), and clinicopathological characteristics were compared using Chi-square and Fisher's exact tests with Cramér's V. Results: Patients had a mean age of 73.2 years; 72.8% were male. Most lesions were in the lower/middle stomach, differentiated (92.2%), depressed (52.9%), and brownish on narrow-band imaging (65.3%). Mean tumor diameter was 13.4 mm. Although 1st lesions were larger, other features showed high concordance (≥ 0.25 Cramér's V) in location, morphology, histology, invasion depth, and coloration. Survival was 94.8% (nine unrelated deaths). Conclusions: Synchronous multiple gastric neoplasms tend to have similar endoscopic and histopathologic features and often occur within the same belt-like region along the short axis of the stomach. This pattern was named boundary equal lesions trends (BELT). When detecting one lesion, considering BELT is essential.

Indexed as

Diagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE)Endoscopic resection (ESD, EMRc, ...)Endoscopy Upper GI TractGI surgeryMalignant strictures

Identifiers

PMID41777338
PMCPMC12951031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.