Evidence map›Paper›PMID 41777251›Full record

ArticleObesities2022

Pilot Associations between Adverse Childhood Experiences, Executive Function, and Brain-Derived Neurotrophic Factor (BDNF) among Adults with Excess Adiposity.

Cindy E Tsotsoros, Madison E Stout, Austin R Medlin, Laurie Wideman, Dolores Vazquez Sanroman, Chibing Tan, T Kent Teague, Misty A W Hawkins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesities, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cindy E TsotsorosDepartment of Human Development & Family Science, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0002-3480-0175
Madison E StoutDepartment of Psychology, Oklahoma State University, Stillwater, OK 74074, USA.ORCID 0000-0002-6379-048X
Austin R MedlinDepartment of Health & Wellness Design, School of Public Health, Indiana University, 1025 E. 7th Street, Bloomington, IN 47405, USA.
Laurie WidemanDepartment of Kinesiology, University of North Carolina Greensboro, Greensboro, NC 27402, USA.ORCID 0000-0001-5100-7657
Dolores Vazquez SanromanOSU Center for Health Sciences, Department of Anatomy & Cell Biology, Tulsa, OK 74107, USA.
Chibing TanIntegrative Immunology Center, University of Oklahoma, Tulsa, OK 74107, USA.
T Kent TeagueIntegrative Immunology Center, University of Oklahoma, Tulsa, OK 74107, USA.
Misty A W HawkinsDepartment of Psychology, Oklahoma State University, Stillwater, OK 74074, USA.

Funding

The Impact of Maternal Adversity and Attachment Security on Infant Stress Reactivity: Prenatal Epigenetic PathwaysP20GM109097 · NIGMS · OSU CENTER FOR HEALTH SCIENCES · PI Dian Yu · 2016 to 2026
$22.8M
Cognitive and Self-Regulatory Mechanisms of Obesity Study (COSMOS)K23DK103941 · NIDDK · OKLAHOMA STATE UNIVERSITY STILLWATER · PI HAWKINS, MISTY · 2015 to 2019
$736k
Differential Impact of ACEs and Aging on Brain HealthR36AG072342 · NIA · OKLAHOMA STATE UNIVERSITY STILLWATER · PI TSOTSOROS, CINDY EILEEN · 2021 to 2021
$69k
NIA NIH HHS R36 AG072342NIDDK NIH HHS K23 DK103941NIGMS NIH HHS P20 GM109097
6 · The paper itself

Abstract

Adverse childhood experiences (ACEs) may predict markers of neurocognitive performance (i.e., executive function; EF) and brain health/plasticity (i.e., brain-derived neurotrophic factor; BDNF). This pilot examined: (1) ACES history and current EF performance, (2) ACEs history and current BDNF levels, and (3) current EF performance and BDNF levels. We hypothesized that higher ACEs would be associated with lower EF scores and that these patterns would be associated with serum BDNF levels. Given the pilot nature of the study, emphasis was placed on effect size vs. significance. Participants were 37 middle-aged women. Higher ACEs were not directly associated with EF scores (

Indexed as

adverse childhood experiencescognitive functionearly life adversityneurotrophic factorneurotrophinsobesityoverweight

Identifiers

PMID41777251
PMCPMC12952787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.