ReviewFrontiers in pharmacology2026
Preclinical approaches to studying liver and kidney fibrosis: models and methodologies.
Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
4 authors.
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Abstract
Organ fibrosis, notably affecting the liver and kidneys, remains a major contributor to global morbidity. This review examines the pathophysiology, molecular mechanisms, and preclinical models used to study hepatic and renal fibrosis. In liver fibrosis, hepatic stellate cell activation, chronic inflammation, and extracellular matrix accumulation are central features, while renal fibrosis involves myofibroblast activation and redox-mediated signaling pathways. The present review highlights both
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