Evidence map›Paper›PMID 41776852›Full record

ArticleKorean journal of radiology2026

Association of T2-Weighted Imaging Features in Invasive Breast Cancer With Clinicopathologic Features and Neoadjuvant Treatment Outcomes.

Inyoung Youn, Yun Ho Roh, Min Jung Kim, Jung Hyun Yoon, Mi-Ri Kwon, Vivian Youngjean Park

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PubMed Full text at PMC Publisher
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Article in Korean journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Inyoung YounDepartment of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-3518-3332
Yun Ho RohBiostatistics Collaboration Unit, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-0841-7161
Min Jung KimDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-4949-1237
Jung Hyun YoonDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-2100-3513
Mi-Ri KwonDepartment of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-8225-3690
Vivian Youngjean ParkDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of Korea. VIVIANPARK0116@yuhs.ac.ORCID https://orcid.org/0000-0002-5135-4058

Funding

Yonsei University College of Medicine 6-2022-0162
6 · The paper itself

Abstract

objectiveTo investigate the associations between T2-weighted imaging (T2WI) features and clinicopathologic characteristics in invasive breast cancer, as well as their relationship with treatment response to neoadjuvant chemotherapy (NAC). MATERIALS AND

methodsThis retrospective study included 179 women with invasive breast cancer who underwent preoperative 3T breast MRI between November 2020 and February 2021. Intratumoral T2 signal intensity (SI) and peritumoral edema were graded on T2WI, and T2 relaxation times were calculated both including and excluding necrotic or cystic areas. T2 relaxation times were compared across T2 SI grades using the Kruskal-Wallis test. Associations between T2 features and clinicopathologic factors were assessed using chi-square tests and logistic regression analyses. In patients who received NAC (n = 68), associations between T2 features and NAC outcomes were also evaluated.

resultsHigher intratumoral T2 SI and peritumoral edema grades were significantly associated with longer T2 relaxation times (

conclusionT2-weighted MRI features were associated with clinicopathologic factors, including clinical T category, HR status, triple-negative subtype, and disease progression during NAC.

Indexed as

Breast NeoplasmsMagnetic Resonance ImagingNeoadjuvant TherapyAdultAgedFemaleHumansMiddle AgedNeoplasm InvasivenessRetrospective StudiesTreatment OutcomeBreast cancerMagnetic resonance imagingNeoadjuvant therapyT2 relaxation timeT2-weighted imaging

Identifiers

PMID41776852
PMCPMC13056451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.