Evidence map›Paper›PMID 41776525›Full record

ReviewSubstance abuse treatment, prevention, and policy2026

Ho'ouna Pono: a 20-year journey of designing, implementing, and sustaining prevention for rural, Indigenous communities.

Kelsie H Okamura, M Asher Cramer, Tessa Palafu, Susana Helm, Francis Dalisay, Zoe Primack, Danielle Carreira Ching, Savannah Goshgarian-Miller, Michelle Liu, Steven Keone Chin and 8 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Substance abuse treatment, prevention, and policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kelsie H OkamuraThe Baker Center for Children and Families, 53 Parker Hill Ave., Boston, MA, 02120, USA. kelsie.okamura@pennmedicine.upenn.edu.
M Asher CramerPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Tessa PalafuThe Baker Center for Children and Families, 53 Parker Hill Ave., Boston, MA, 02120, USA.
Susana HelmJohn A. Burns School of Medicine, University of Hawai'i at Mānoa, 677 Ala Moana Blvd., Honolulu, HI, 96813, USA.
Francis DalisayCollege of Journalism and Communications, University of Florida, 2096 Weimer Hall, 1885 Stadium Road, Gainsville, FL, 32611, USA.
Zoe PrimackPerelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA.
Danielle Carreira ChingThe Baker Center for Children and Families, 53 Parker Hill Ave., Boston, MA, 02120, USA.
Savannah Goshgarian-MillerPerelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA.
Michelle LiuThe Baker Center for Children and Families, 53 Parker Hill Ave., Boston, MA, 02120, USA.
Steven Keone ChinPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Sarah Momilani MarshallThompson School of Social Work & Public Health, University of Hawai'i at Mānoa, Gartley Hall, 2430 Campus Road, Honolulu, HI, 96822, USA.
Paula Angela SaladinoPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Zarek K KonPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Sarah D SongPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Reilynn YamanePerelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA.
Nadia Yoshizumi-KimPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Cerila C RapadasPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.
Scott K OkamotoPopulation Sciences in the Pacific Program, University of Hawai'i Cancer Center, 701 Ilalo St., Honolulu, HI, 96813, USA.

Funding

University of Guam/Cancer Research Center of Hawaii Partnership (1 of 2)U54CA143727 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI THADDEUS A HERZOG · 2009 to 2026
$19.1M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI BRAUN, KATHRYN LENZNER · 2021 to 2025
$15.5M
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian YouthR01DA054215 · NIDA · UNIVERSITY OF HAWAII AT MANOA · PI Scott Kiyoshi Okamoto · 2022 to 2026
$2.9M
Community-driven drug prevention implementation strategies for Native Hawaiian and Pacific Islander youth in rural Hawai'iDP1DA061311 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI Kelsie Okamura · 2024 to 2026
$2.5M
The Development and Evaluation of the Ho'ouna Pono Drug Prevention CurriculumR01DA037836 · NIDA · HAWAII PACIFIC UNIVERSITY · PI OKAMOTO, SCOTT KIYOSHI · 2015 to 2018
$1.6M
The Implementation, Adoption, and Sustainability of Ho'ouna PonoR34DA046735 · NIDA · HAWAII PACIFIC UNIVERSITY · PI OKAMOTO, SCOTT KIYOSHI · 2019 to 2021
$812k
Ecological Factors and Drug Use of Native Hawaiian YouthK01DA019884 · NIDA · HAWAII PACIFIC UNIVERSITY · PI OKAMOTO, SCOTT KIYOSHI · 2006 to 2011
$809k
The Development of a Video-Enhanced Drug Prevention Program for Rural Native HawaR34DA031306 · NIDA · HAWAII PACIFIC UNIVERSITY · PI OKAMOTO, SCOTT KIYOSHI · 2011 to 2013
$558k
NCI NIH HHS U54 CA143727NIDA NIH HHS DP1 DA061311NIDA NIH HHS K01 DA019884NIDA NIH HHS L60 DA059132NIDA NIH HHS R01 DA037836NIDA NIH HHS R01 DA054215NIDA NIH HHS R34 DA031306NIDA NIH HHS R34 DA046735NIGMS NIH HHS U54 GM138062
6 · The paper itself

Abstract

backgroundNumerous research studies indicate that Native Hawaiian and Pacific Islander (NHPI) youth report disproportionately higher substance use rates than other ethnic groups, as well as higher adverse effects associated with their use. Nonetheless, there has been a historical lack of evidence-based, culturally relevant interventions designed to prevent NHPI substance use. This article describes the trajectory of school-based, culturally grounded substance use prevention research for NHPI youth funded by the National Institute on Drug Abuse over the past two decades.

methodsA review and synthesis of published research documenting the development, evaluation, implementation, and adaptation of the Hoʻouna Pono (HP) program is presented. The interconnectedness of separate funded research studies is highlighted.

resultsThe HP program was developed and evaluated through 5 interconnected studies—a pre-prevention study, a pilot study, an efficacy trial, an implementation study, and an e-cigarette adaptation study. The program was also adapted to different regions through two complementary studies—a Guam adaptation (Fuestan Manhoben) and a Windward Oʻahu hybrid implementation trial (Mohala Na Pua).

conclusionsThe life course of the HP program may serve as a model for the development of culturally grounded prevention for under-researched and underserved youth populations. The program is a foundation for future substance use prevention adaptations across Hawaiʻi and the Pacific. CLINICAL TRIAL: Not applicable.

Indexed as

Native Hawaiian or Pacific IslanderRural PopulationSubstance-Related DisordersAdolescentHawaiiHumansProgram DevelopmentProgram EvaluationImplementationNative HawaiianPacific IslanderPreventionSubstance useYouth

Identifiers

PMID41776525
PMCPMC13127057

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.