Evidence map›Paper›PMID 41776498›Full record

ArticleBMC public health2026

Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: a scoping review.

Gugulethu Ncube, Perez Livias Moyo, Taremba Chirigo

Abstract readScoping Review
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gugulethu NcubeDepartment of Environmental Health, Faculty of Environmental Science, National University of Science and Technology, Corner Cecil Avenue and Gwanda Road, P.O. Box AC 939, Ascot, Bulawayo, Zimbabwe.
Perez Livias MoyoDepartment of Environmental Health, Faculty of Environmental Science, National University of Science and Technology, Corner Cecil Avenue and Gwanda Road, P.O. Box AC 939, Ascot, Bulawayo, Zimbabwe. perezlivias1997@gmail.com.ORCID http://orcid.org/0009-0005-7501-0611
Taremba ChirigoDepartment of Environmental Health, Faculty of Environmental Science, National University of Science and Technology, Corner Cecil Avenue and Gwanda Road, P.O. Box AC 939, Ascot, Bulawayo, Zimbabwe.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including U = U (Undetectable = Untransmittable). Effective interventions are crucial to support these couples in managing their relationships, promoting treatment adherence, and reducing the risk of HIV transmission. This scoping review aims to identify, map, and evaluate the range of interventions designed to support thriving and the maintenance of healthy relationships among HIV serodiscordant couples.

methodsA comprehensive search strategy was employed across six electronic databases (PubMed, Scopus, Google Scholar, Web of Science, PsycINFO, and CINAHL) for literature published between January 2014 and March 2025. The search included explicit terms for all 49 Sub-Saharan African countries. Study selection was guided by the Population, Concept, Context (PCC) framework for scoping reviews. A total of 17 studies met the inclusion criteria.

resultsThe review synthesises interventions into three primary categories: couples-based (n = 11 sources, 65%), community-based (n = 8 sources, 47%), and positive psychology interventions (n = 4 sources, 24%). Key barriers, included internal stigma, gender inequalities, and socio-economic challenges. Key facilitators included comprehensive education, community outreach, and supportive couple dynamics. Geographic distribution was uneven: East Africa (n = 7), Southern Africa (n = 6), West Africa (n = 2), Central Africa (n = 1), and global/multi-regional reviews (n = 4). Most primary studies focused on heterosexual couples (85%), with limited evidence for same-sex couples.

conclusionThe findings accentuate the necessity of multi-component, culturally tailored interventions that integrate biomedical, psychosocial, and structural approaches to improve health outcomes and relationship satisfaction for serodiscordant couples. This synthesis provides a foundation for developing evidence-informed interventions and highlights critical gaps for future research.

Indexed as

HIV InfectionsHIV SeropositivitySexual PartnersAfrica South of the SaharaFemaleHumansMaleSub-Saharan African PeopleHIV and AIDSHIV serodiscordant relationshipsInterventionsScoping reviewThriving

Identifiers

PMID41776498
PMCPMC13063446

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.