Evidence map›Paper›PMID 41776475›Full record

ArticleBMC complementary medicine and therapies2026

Antibacterial and antioxidant activities of Inula confertiflora extracts.

Eshetu Wolde Mekonen, Sisay Awoke Endalew, Yirga Adugna Ferede, Gedefaw Wubie Birhan

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eshetu Wolde MekonenDepartment of Environmental health, College of medicine and health science, Wollo University, Desssie, Ethiopia. eshewold457@gmail.com.
Sisay Awoke EndalewDepartment of chemistry, College of natural sciences, Wollo University, Dessie, Ethiopia.
Yirga Adugna FeredeDepartment of chemistry, College of natural sciences, Wollo University, Dessie, Ethiopia.
Gedefaw Wubie BirhanDepartment of Biology, School of Bioscience and Technology, College of Natural Science, Wollo University, Dessie, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntimicrobial-resistant pathogenic microorganisms are disease causing microbes that cause several diseases in humans, animals, and plants. Currently, these microorganisms cause more than a quarter of the reported diseases worldwide. The other current global health risk is the imbalance generation of free radicals in human physiology, which exposes several millions to oxidative stress diseases like Alzheimer, Cancer, and Diabetes.

objectiveThe objective of this study was to evaluate the antibacterial and antioxidant activities of Inula confertiflora roots, stems, and leaves extracts.

methodThe methanolic, ethyl acetate, and petroleum ether extracts of the roots, stems, and leaves of this plant were separately evaluated against the Gram-positive bacteria strains Enterococcus faecalis, Staphylococcus aureus, and Gram-negative bacteria Klebsiella pneumonia using the agar well diffusion method. Each crude extract was also evaluated by an invitro antioxidant activity test against DPPH free radical reagent.

resultThe crude extrats showed moderate to high activities against two Gram-positive bacterial strains, S. aureus and E. faecalis. The petroleum ether extract of the leaves showed the highest activity (39.97 ± 0.12 mm inhibition diameter) against S. aureus. All crude extracts also showed strong free radical scavenging activity, with a maximum percentage scavenging value. The root petroleum ether extracts showed 99.18 ± 0.06% scavenging activity at 1000 (µg/ml) concentration.

conclusionExtracts from this plant are potentially effective against S. aureus and E. faecalis; they also have strong free radical scavenging activities.

Indexed as

Anti-Bacterial AgentsAntioxidantsInulaPlant ExtractsEnterococcus faecalisGram-Positive BacteriaKlebsiella pneumoniaeMicrobial Sensitivity TestsPlant LeavesPlant RootsStaphylococcus aureusAnti-Bacterial AgentsAntioxidantsPlant ExtractsAntibacterialAntioxidantInula confertiflora

Identifiers

PMID41776475
PMCPMC13063460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.