ArticleBMC genomics2026
Mobile genetic elements drive the evolution and multidrug resistance of Salmonella infantis along the United States poultry production line.
Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundSalmonella is the primary enteric pathogen related to foodborne illnesses worldwide, posing significant public health concerns. Amongst the diversity and pathogenicity of over 2000 Salmonella serovars, Salmonella Infantis (S. Infantis) ranks among the top Salmonella serovars implicated in foodborne outbreaks, with thousands of reported cases annually in the United States. Moreover, the incidence of S. Infantis infections has spread rapidly worldwide from the U.S. to Europe, where more than 50% of isolated S. Infantis strains have developed antibiotic resistance. Previous studies have demonstrated that antibiotic resistance genes (ARGs), particularly those carried by plasmids, contribute to the persistence and spread of multipledrug-resistant (MDR) Salmonella strains in various environments. However, the information regarding the multidrug resistance and spread of S. Infantis is scarce. Hence, the objectives of this study were to characterize antibiotic-resistant S. Infantis isolated from the poultry production line in the United States and to examine the correlation between mobile genetic elements and bacterial resistome evolution.
resultsA total of 9 S. Infantis strains were isolated from poultry production lines in 2022, including comminuted chicken, raw intact/nonintact chicken, and chicken carcass. These strains were further subject to antimicrobial susceptibility tests, whole-genome sequencing, and bioinformatic analysis. Most strains were MDR and phenotypically resistant to five or more antibiotics, such as Streptomycin and Tetracycline. The complete bacterial genome results showed that all isolates had a dsDNA chromosome with a GC content of 52.3% and an average genome size of 4,730 kb, belonging to the sequence type 32. The genomic characterization of S. Infantis isolates revealed that each strain contained one IncFIB mega-plasmid with lengths from 289 to 327 kb. Five or more ARGs were detected in each strain, most of which were located in the mega-plasmids and bordered by diverse mobile genetic elements, including transposons, integrons, and prophages. The common ARGs present in the mega-plasmids included bla
conclusionThese findings reveal the genomic features and antimicrobial resistance profiles of S. Infantis strains from poultry production lines in the United States, indicating the potential of mobile genetic elements-driven S. Infantis resistome development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.