Evidence map›Paper›PMID 41776375›Full record

ArticleKorean journal of ophthalmology : KJO2026

Comparison of Clinical Outcomes of Intravitreal 0.625% Povidone-Iodine versus Antibiotic Injection for Postoperative Endophthalmitis.

Su Min Lee, Seungwoo Lee, Woo Jung Chae, Han Sang Park

Abstract readComparative Study
In one paragraph

Article in Korean journal of ophthalmology : KJO, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Su Min LeeDepartment of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea.
Seungwoo LeeDepartment of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. swlee@dongguk.ac.kr.
Woo Jung ChaeDepartment of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea.
Han Sang ParkNune Eye Hospital, Daegu, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative endophthalmitis is a sight-threatening intraocular infection requiring prompt treatment. This study aimed to compare the clinical outcomes of intravitreal 0.625% povidone-iodine (PI) injection with intravitreal antibiotic injection for the treatment of postoperative endophthalmitis.

methodsA retrospective review of 40 eyes diagnosed with postoperative endophthalmitis was conducted. Patients were divided into two groups: group 1 received intravitreal 0.625% PI injection (0.1 mL), while group 2 received intravitreal antibiotic injection. Clinical data, including best-corrected visual acuity (BCVA), intraocular pressure, the number of intravitreal injections, duration of anterior chamber hypopyon, and the need for pars plana vitrectomy (PPV), were analyzed.

resultsGroup 1 (24 eyes) showed significant improvements in BCVA posttreatment (mean, 1.04 ± 0.95 logMAR; p < 0.001) compared to group 2 (16 eyes; mean, 1.26 ± 0.99 logMAR; p = 0.092). Severe visual impairment (BCVA < 10 / 100) was significantly less frequent in group 1 (25.0%) than in group 2 (62.5%) (p = 0.025). The mean duration of hypopyon was shorter in group 1 (2.6 ± 2.2 days) compared to group 2 (6.4 ± 7.3 days, p = 0.048). Fewer intravitreal injections (p = 0.002) and PPV (p = 0.002) were required in group 1.

conclusionsIntravitreal 0.625% PI injection was associated with fewer intravitreal injections, shorter hypopyon duration, and more favorable visual outcome-related measures, including significant visual improvement from baseline and a lower frequency of severe visual impairment, compared with intravitreal antibiotic treatment. These findings suggest that PI may be considered a safe and effective initial treatment option for postoperative endophthalmitis. Further prospective studies are needed to validate these results.

Indexed as

Anti-Bacterial AgentsEndophthalmitisEye Infections, BacterialPostoperative ComplicationsPovidone-IodineAgedAnti-Infective Agents, LocalFemaleFollow-Up StudiesHumansIntravitreal InjectionsMaleMiddle AgedRetrospective StudiesTreatment OutcomeVisual AcuityAnti-Bacterial AgentsAnti-Infective Agents, LocalPovidone-IodineEndophthalmitisIntravitreal injectionsPovidone-iodine

Identifiers

PMID41776375
PMCPMC13279922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.