Evidence map›Paper›PMID 41776319›Full record

Articlenpj antimicrobials and resistance2026

Genomic survey uncovers the emergence of a multidrug-resistant dominant lineage in Proteus mirabilis populations.

Tiejun Zhang, Hongcheng Wei, Zijing Ju, Qin Wang, Jinpeng Li, Renqiao Wen, Jie Wu, Hongning Wang, Changwei Lei

Abstract read
In one paragraph

Article in npj antimicrobials and resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Pangenome analysis ofAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tiejun Zhang *College of Life Sciences, Sichuan University, Chengdu, China.
Hongcheng Wei *College of Life Sciences, Sichuan University, Chengdu, China.
Zijing JuCollege of Life Sciences, Sichuan University, Chengdu, China.
Qin WangCollege of Life Sciences, Sichuan University, Chengdu, China.
Jinpeng LiCollege of Life Sciences, Sichuan University, Chengdu, China.
Renqiao WenCollege of Life Sciences, Sichuan University, Chengdu, China.
Jie WuCollege of Life Sciences, Sichuan University, Chengdu, China.
Hongning WangCollege of Life Sciences, Sichuan University, Chengdu, China. hongningwang@scu.edu.cn.
Changwei LeiCollege of Life Sciences, Sichuan University, Chengdu, China. leichangwei@scu.edu.cn.

Funding

earmarked fund for China Agriculture Research System CARS-40-K14National Key Research and Development Program of China 2022YFD1800400Natural Science Foundation of Sichuan Province 2025ZNSFSC0209
6 · The paper itself

Abstract

Proteus mirabilis, a Gram-negative bacterium renowned for its distinctive swarming motility, is a major causative agent of catheter-associated urinary tract infections (CAUTIs) and nosocomial complications. While advances in sequencing technologies have generated extensive genomic data, critical gaps persist in understanding the global population structure and evolutionary drivers of antimicrobial resistance in this pathogen. To address this knowledge gap, we performed a phylogenomic analysis of 1,142 P. mirabilis genomes spanning 34 countries and 16 ecological niches. Our investigation identified a dominant multidrug-resistant lineage (Cluster-1) carrying significantly elevated antimicrobial resistance gene burdens, including high-prevalence carbapenemase genes bla

Identifiers

PMID41776319
PMCPMC12957351

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.