Evidence map›Paper›PMID 41776146›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2026

Estimating the percentage and number of people with indications for HIV pre-exposure prophylaxis (PrEP) within two key populations, Canada, 2021.

Qiuying Yang, Hong-Xing Wu, Nathan Lachowsky, Joseph Cox, Ben Klassen, Herak Apelian, Simone Périnet, Janelle Elliott, Anson Williams, Laurence Campeau and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qiuying YangPublic Health Agency of Canada, Ottawa, ON, Canada. qiuying.yang@phac-aspc.gc.ca.ORCID http://orcid.org/0009-0003-7939-3029
Hong-Xing WuPublic Health Agency of Canada, Ottawa, ON, Canada.
Nathan LachowskyCommunity-Based Research Centre, Vancouver, BC, Canada.
Joseph CoxPublic Health Agency of Canada, Ottawa, ON, Canada.
Ben KlassenCommunity-Based Research Centre, Vancouver, BC, Canada.
Herak ApelianPublic Health Agency of Canada, Ottawa, ON, Canada.
Simone PérinetPublic Health Agency of Canada, Ottawa, ON, Canada.
Janelle ElliottPublic Health Agency of Canada, Ottawa, ON, Canada.
Anson WilliamsPublic Health Agency of Canada, Ottawa, ON, Canada.
Laurence CampeauPublic Health Agency of Canada, Ottawa, ON, Canada.
Tyrone CurtisUniversity of Victoria, Victoria, BC, Canada.
Marcus WongPublic Health Agency of Canada, Ottawa, ON, Canada.
Marene GataliPublic Health Agency of Canada, Ottawa, ON, Canada.
Nashira PopovicPublic Health Agency of Canada, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHIV pre-exposure prophylaxis (PrEP) is proven effective for HIV prevention and recommended for individuals at ongoing and high risk of HIV, including gay, bisexual, and other men who have sex with men (GBMSM) and people who inject drugs (PWID). We used existing national survey data to measure PrEP need in both populations and calculate percentages of use among those meeting indications within each group.

methodsWe conducted a secondary data analysis of nationally representative data to estimate the percentage of GBMSM and PWID meeting PrEP indications based on 2017 Canadian guidelines. We applied these percentages to recent population size estimates for both groups to estimate the number of people having PrEP indications in each group. Where available, we also used survey data to determine the percentage of people with indications who were not taking PrEP at the time of the survey.

resultsAn estimated 24.1% (95% CI 13.3-39.7%) or 99,300 (95% CI 54,800-163,600) of GBMSM had PrEP indications in Canada as of 2021. The corresponding percentage and number for PWID were 22.3% (20.8-22.8%) and 22,400 (20,900-23,900). Two-thirds of GBMSM participants (Sex Now 2019 and 2021) who had PrEP indications were not taking PrEP at the time of the surveys. None of the participants with PrEP indication in the Tracks survey (2017-2019) among PWID reported PrEP use.

conclusionIn Canada, the estimated number of people with PrEP indications among GBMSM and PWID far exceeded documented levels of use. Uptake of PrEP was lower among PWID compared to GBMSM. Efforts to improve PrEP access and uptake could help reduce HIV transmission in Canada.

Indexed as

HIV pre-exposure prophylaxis (PrEP)HIV preventionIndicationsMen who have sex with men (GBMSM)People who inject drugs (PWID)

Identifiers

PMID41776146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.