Evidence map›Paper›PMID 41776079›Full record

ArticleOral and maxillofacial surgery2026

Biomechanical rationale for a hybrid mIVSRO-SSRO surgical strategy in mandibular asymmetry: a retrospective cohort study.

Nodoka Nagae, Shogo Kikuta, Joe Iwanaga, Jingo Kusukawa

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Article in Oral and maxillofacial surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Nodoka NagaeDental and Oral Medical Center, Kurume University School of Medicine, 67, Asahi-Machi, Kurume, Fukuoka, 830-0011, Japan.
Shogo KikutaDental and Oral Medical Center, Kurume University School of Medicine, 67, Asahi-Machi, Kurume, Fukuoka, 830-0011, Japan. kikuta_shougo@kurume-u.ac.jp.
Joe IwanagaDental and Oral Medical Center, Kurume University School of Medicine, 67, Asahi-Machi, Kurume, Fukuoka, 830-0011, Japan.
Jingo KusukawaDental and Oral Medical Center, Kurume University School of Medicine, 67, Asahi-Machi, Kurume, Fukuoka, 830-0011, Japan.

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6 · The paper itself

Abstract

purposeThe surgical correction of mandibular asymmetry presents a biomechanical challenge regarding iatrogenic condylar torque on the temporomandibular joint (TMJ). This study aimed to characterize the unique biomechanical effects and clinical outcomes of a hybrid modified intraoral vertico-sagittal ramus osteotomy (mIVSRO) and sagittal split ramus osteotomy (SSRO) strategy, using bilateral SSRO (BSSRO) and unilateral SSRO (USSRO) as established reference techniques.

methodsThis retrospective study included 120 patients with mandibular asymmetry treated between January 2016 and April 2024. Inclusion criteria were skeletal class III or open bite requiring mandibular osteotomy. Patients with syndromes, prior TMJ surgery, or incomplete data were excluded. The cohort was stratified into three groups: BSSRO (n = 98), USSRO (n = 8), and Hybrid (n = 14). Primary outcomes were the 6-month postoperative change in the condylar long axis angle and the change in TMJ symptoms (improved, unchanged, or worsened). Analysis of covariance (ANCOVA) and multivariate ordinal logistic regression were used for statistical analysis.

resultsThe Hybrid group demonstrated significant and unique external condylar rotation on the deviated side (mean adjusted angle: 11.81 ± 0.90°), whereas both the BSSRO (16.46 ± 0.34°, p < .001) and USSRO (16.07 ± 1.18°, p = 0.013) groups exhibited internal rotation. High rates of TMJ symptom improvement were observed in the Hybrid (83.3%) and BSSRO (65.1%) groups, but the intergroup difference was not statistically significant (p = 0.144). Multivariate analysis identified preoperative TMJ symptoms as the sole significant predictor of postoperative improvement (p < .001), irrespective of surgical technique.

conclusionThe hybrid mIVSRO-SSRO technique produces a distinct biomechanical outcome by inducing external condylar rotation on the deviated side, contrasting with the internal rotation observed in BSSRO and USSRO. While this rotational difference was significant, high rates of symptom improvement were observed across groups without a statistically significant difference (p = 0.144), suggesting that patient-specific factors may play a larger role in clinical outcomes than the osteotomy design alone.

Indexed as

Facial AsymmetryMalocclusion, Angle Class IIIMandibleOsteotomy, Sagittal Split RamusAdultBiomechanical PhenomenaFemaleHumansMaleMandibular CondyleOpen BiteRetrospective StudiesTreatment OutcomeIVSROMandibular asymmetryOrthognathic surgerySSROTemporomandibular jointUSSRO

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.