ArticleNPJ cardiovascular health2025
A rapid 0/1 h algorithm for suspected non-ST-segment elevation myocardial infarction using high-sensitivity cardiac troponin I.
Article in NPJ cardiovascular health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Clinical Gray Zones of Cardiac Troponin Interpretation in the Emergency Department: When Increased Concentrations Do Not Equal Acute Coronary Syndrome.Journal of clinical medicine · 2026Review
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Authors and funding
9 authors.
Funding
Abstract
We aimed to derive a new high-sensitivity cardiac troponin I Access (hs-cTnI-Access) 0/1h-algorithm suitable for Chinese patients. In the multi-centre study, we enrolled 369 patients with suspected non-ST-segment elevation myocardial infarction (NSTEMI). Following an adjustment, AnZhen hs-cTnI-Access 0/1h-algorithm was established with rule-in cut-off values of 0 h ≥ 50 pg/mL or Δ1h ≥ 18.0 pg/mL and rule-out cut-off values of 0 h < 3 pg/mL or 0 h < 4 pg/mL and Δ1h < 3.0 pg/mL. These revised cutoffs presented a negative predictive value (NPV) of 99.46% (95% CI,97.02-99.91%) and a sensitivity of 98.81% (95% CI,93.56-99.79%), and also resulted in a positive predictive value (PPV) of 86.42% (95% CI,77.30-92.24%) and a specificity of 96.14% (95% CI,93.22-97.83%), both of which were superior to those of the ESC 0/1 h algorithm. The new hs-cTnI-Access 0/1 h-algorithm adjusted for Chinese data is promising for improving both safety and efficacy in Chinese patients.
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Registered trials
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