ArticleNPJ cardiovascular health2024
Culprit lesion characteristics and prognosis in STEMI with cold onset: an OCT study.
Article in NPJ cardiovascular health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
Authors and funding
8 authors.
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Abstract
Cold temperature exposure is associated with increased cardiovascular morbidity. However, limited research has explored plaque characteristics and prognosis in ST-segment elevation myocardial infarction (STEMI) patients diagnosed in cold temperatures. In the current study, 517 STEMI patients who underwent coronary optical coherence tomography examination were included and divided according to a median of the ambient temperature(11.5 °C). Our result shows that the cold temperature group exhibited higher proportions of plaque rupture, 78.1%, compared to 68.8% in the warm temperatures group. Besides, patients in the cold temperature group showed thinner minimum fibrous cap thickness (60.0 vs. 70.0 μm, p = 0.035). Furthermore, the cold temperature group showed a higher incidence rate of major adverse cardiac events (MACE), which includes cardiac death, recurrent nonfatal myocardial infarction, stroke, or hospitalization for heart failure (15.7% vs. 9.7%, p = 0.041). Moreover, cold temperature exposure at the onset independently predicted MACE (HR1.83 [95%CI 1.06-3.14], p = 0.029).
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