Evidence map›Paper›PMID 41775957›Full record

ReviewNpj biological timing and sleep2025

Motivation meets sleep: tuning arousal via nucleus accumbens and Basal Ganglia circuits.

Fares J P Sayegh, Patricia Bonnavion

Abstract readReview
In one paragraph

Review in Npj biological timing and sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fares J P SayeghUniversité Libre de Bruxelles (ULB), ULB Neuroscience Institute, Laboratory of Neurophysiology, Brussels, Belgium.
Patricia BonnavionUniversité Libre de Bruxelles (ULB), ULB Neuroscience Institute, Laboratory of Neurophysiology, Brussels, Belgium. Patricia.Bonnavion@ulb.be.

Funding

Fonds de la Recherche Scientifique (F.R.S.-FNRS) CR postdoctoral fellowship (grant 40017148)F.R.S.-FNRS MIS Starting Grant (grant 40008307)
6 · The paper itself

Abstract

Traditionally linked to motor control and motivation, the basal ganglia, particularly the nucleus accumbens (NAc), are now recognized as central to sleep-wake regulation. Rodent studies highlight the NAc as a hub where motivation, arousal, and sleep homeostasis converge, mediated by D1- and D2-MSN activity. This review examines its organization and circuits, emphasizing roles in vigilance, valence, and associative learning, and exploring emerging hypotheses on its contribution to sleep-related cognition and disorders.

Identifiers

PMID41775957
PMCPMC12912427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.