ReviewNpj biological timing and sleep2025
Motivation meets sleep: tuning arousal via nucleus accumbens and Basal Ganglia circuits.
Review in Npj biological timing and sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
Abstract
Traditionally linked to motor control and motivation, the basal ganglia, particularly the nucleus accumbens (NAc), are now recognized as central to sleep-wake regulation. Rodent studies highlight the NAc as a hub where motivation, arousal, and sleep homeostasis converge, mediated by D1- and D2-MSN activity. This review examines its organization and circuits, emphasizing roles in vigilance, valence, and associative learning, and exploring emerging hypotheses on its contribution to sleep-related cognition and disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.