Evidence map›Paper›PMID 41775455›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie

Stimulant drug misuse in patients presenting to level 1 trauma centres: a retrospective analysis of 80 000 patients in Canada and the United States.

Caroline Cristofaro, Ellie B Pinsker, Timothy R Daniels, Amit Atrey, Amir Khoshbin, Mansur Halai

Abstract read
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caroline CristofaroFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai) caroline.cristofaro@mail.utoronto.ca.
Ellie B PinskerFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai).
Timothy R DanielsFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai).
Amit AtreyFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai).
Amir KhoshbinFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai).
Mansur HalaiFrom the Department of Surgery, University of Toronto, Toronto, Ont. (Cristofaro, Daniels, Khoshbin, Halai); the Division of Orthopaedic Surgery, Department of Surgery, St. Michael's Hospital, Toronto, Ont. (Pinsker, Daniels, Khoshbin, Atrey, Halai).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite increasing global misuse of stimulant drugs, there is a paucity of literature regarding stimulant use among trauma patients. The primary aim of this study was to assess hospital mortality among patients with stimulant intoxication who presented to level 1 trauma centres in Canada and the United States. Secondary outcomes included emergency department mortality, hospital length of stay, and admission to the intensive care unit (ICU).

methodsThis is a retrospective analysis of data from the Trauma Quality Improvement Program, including patients presenting emergently to participating level 1 trauma centres from January 2017 to December 2018. We included patients aged 19 to 88 years who had positive toxicology to stimulant drugs or negative toxicology to all drugs. We adjusted for patient demographic factors in the analysis.

resultsWe included 89 130 patients, with 10 017 patients (11.2%) having a positive screen for stimulants. The mean age in the stimulants cohort was 42.0 years, with a 75.9% male preponderance and mean Injury Severity Score of 9. The control cohort was older, with a mean age of 55 years, and a smaller proportion of males (63.0%,

conclusionStimulant misuse is a relevant issue in the trauma population, associated with increased hospital length of stay, but no significant difference in mortality. By addressing stimulant intoxication in trauma patients, health care providers can work toward improving patient outcomes and reducing the associated health care burden.

Indexed as

Central Nervous System StimulantsDrug MisuseHospital MortalitySubstance-Related DisordersTrauma CentersWounds and InjuriesAdultAgedAged, 80 and overCanadaEmergency Service, HospitalFemaleHumansInjury Severity ScoreIntensive Care UnitsLength of StayCentral Nervous System Stimulants

Identifiers

PMID41775455
PMCPMC12965664

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.