Evidence map›Paper›PMID 41775161›Full record

ArticlePoultry science2026

Generation of chimeric chickens resistant to infection by avian leukemia virus subgroups A, B, D, E, and K through primordial germ cells.

Gengsheng Xiao, Weiguo Chen, Xiaoling Chen, Ying Huang, Tingxi Pan, Sheng Chen, Yongsen Wen, Hongxin Li, Xinheng Zhang, Qingmei Xie

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gengsheng XiaoState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Weiguo ChenState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Xiaoling ChenState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Ying HuangSchool of Education, Arts, Design & Architecture, University of New South Wales, Sydney, 2052, Australia.
Tingxi PanState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Sheng ChenState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Yongsen WenState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China; Guangdong AiHealth Biotechnology Co., Ltd., Qingyuan, 511899, PR China.
Hongxin LiState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Xinheng ZhangState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China.
Qingmei XieState Key Laboratory of Swine and Poultry Breeding Industry & Guangdong Laboratory for Lingnan Mod-ern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Provincial Key Lab of AgroAnimal Genomics and Molecular Breeding, College of Animal Sci-ence, South China Agricultural University, Guangzhou, 510642, China; Joint International Research Laboratory of Genetic Resistance to Avian Diseases, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China; Key Laboratory of Animal Health Aquaculture and Environmental Control, Guangdong, Guangzhou, 510642, PR China. Electronic address: qmx@scau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avian leukosis virus (ALVs), an oncogenic retrovirus, induces immunosuppression and various tumors in chickens, posing a severe global threat to poultry health and causing substantial economic losses. Natural resistance alleles, notably tva

Indexed as

Avian LeukosisAvian Leukosis VirusChickensChimeraDisease ResistanceGerm CellsPoultry DiseasesAnimalsChick EmbryoFemaleMaleAvian leukemia virusChimera chickenMicroinjectionPrimordial germ cell

Identifiers

PMID41775161
PMCPMC12969617

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.