Evidence map›Paper›PMID 41774880›Full record

ArticleJCO oncology practice2026

Impact of a Precision Medicine Navigator on Genomic Test Utilization in Black Patients With Prostate Cancer.

Alexander J Allen, Bansi Savla, Claudia Datnow-Martinez, William Mendes, Sophia C Kamran, Stefan Ambs, Zachery Keepers, Caitlin Eggleston, Kaysee Baker, Jason K Molitoris and 15 more

Abstract read
In one paragraph

Article in JCO oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Alexander J AllenDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0009-0000-2863-5233
Bansi SavlaDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Claudia Datnow-MartinezDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
William MendesDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Sophia C KamranMassachusetts General Hospital, Boston, MA.ORCID 0000-0001-9283-6515
Stefan AmbsCenter for Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD.
Zachery KeepersDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0009-0008-8730-5435
Caitlin EgglestonDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Kaysee BakerDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Jason K MolitorisDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-8221-1631
Matthew J FerrisDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0003-0402-4707
Akshar N PatelDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Zaker H RanaDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Dan KunaprayoonDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Jack J HongDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Rashmi K BendaDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Wendla K CitronDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Elai DavicioniVeracyte Biosciences, San Diego, CA.
Mark V MishraDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-2588-1575
Soren M BentzenDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-7444-7564
Taofeek K OwonikokoUniversity of Maryland Greenebaum Cancer Center, Baltimore, MD.ORCID 0000-0002-7724-7728
William F RegineDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.
Young KwokDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0003-1484-8507
Phuoc T TranDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0002-0147-0376
Melissa A L VyfhuisDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD.ORCID 0000-0003-4612-7341

Funding

Resource Sharing CoreU54CA273956 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Luigi Marchionni · 2022 to 2026
$8.9M
NCI NIH HHS U54 CA273956
6 · The paper itself

Abstract

purposeAs oncologic precision medicine develops, there is concern that tumor genomic profiling among Black patients and other underrepresented demographics will lag and amplify health disparities. We evaluate whether a precision medicine navigator (PMN), a clinical navigator specialized in obtaining tumor genomic testing for patients, is associated with increased genomic testing rates and whether this is the case among Black patients and other disadvantaged groups.

methodsWe retrospectively reviewed prostate cancer consults within one health care system from November 2, 2021, to January 2, 2023. We compared the proportion of patients who received genomic testing in the 7 months before the PMN start (pre-PMN) to the 7 months afterward (post-PMN). Binary logistic regression was used to calculate the odds of receiving testing.

resultsThe sample included 693 patients, 311 pre-PMN and 382 post-PMN. Racial distribution and clinical stage were well-balanced between the pre- and post-PMN groups. From pre- to post-PMN, the proportion of patients receiving testing increased from 18% to 70% (

conclusionFor patients with prostate cancer, the presence of a PMN is associated with increased rates of genomic testing overall, including among Black patients and other groups that experience health inequities. Utilization post-PMN was significantly lower in Black patients compared with non-Black patients. More research is needed into why Black patients show lower rates of genomic testing.

Identifiers

PMID41774880
PMCPMC13310370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.