ReviewThe Journal of infectious diseases2026
What's Hot in HIV in 2025-A Basic and Translational Science Review From IDWeek 2025.
Review in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Advances in basic and translational human immunodeficiency virus (HIV-1) research have refined our understanding of viral persistence while informing new strategies aimed at prevention and durable virologic control. Here, we present an overview of selected advances in HIV vaccine development, cure-directed strategies, and new insights into the mechanisms of HIV persistence, highlighting key basic and translational studies published over the past year and featured in What's Hot in HIV Basic Science 2025. Notable progress includes promising results in germline-targeting and sequential immunization for the induction of broadly neutralizing antibody precursors, a better understanding of the mechanisms of reservoir persistence, and encouraging signals that immune-based strategies can lead to postintervention control. Collectively, these insights emphasize the value of experimental medicine trials and underscore a shift toward more precise, mechanism-informed strategies for HIV prevention and cure, pointing to a future in which durable virologic control may be achievable through rationally designed combination approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.