Evidence map›Paper›PMID 41774339›Full record

SynthesisMedical & biological engineering & computing2026

Hardware and software design trends and considerations in gamified stroke rehabilitation: Results from a systematic review.

Juan J Sánchez-Gil, Aurora Sáez Manzano, Juan José Ochoa-Sepúlveda, Laura Muñoz-Millán, David Cáceres-Gómez, Rafael López-Luque, Eduardo Cañete-Carmona

Abstract readSystematic Review
In one paragraph

Synthesis in Medical & biological engineering & computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan J Sánchez-GilDepartamento de Ingeniería Electrónica y de Computadores, Universidad de Córdoba, Edificio Leonardo Da Vinci, Campus de Rabanales, Córdoba, 14071, España. sanchezgil@uco.es.ORCID http://orcid.org/0009-0000-1401-0910
Aurora Sáez ManzanoDepartamento de Ingeniería Electrónica y de Computadores, Universidad de Córdoba, Edificio Leonardo Da Vinci, Campus de Rabanales, Córdoba, 14071, España.
Juan José Ochoa-SepúlvedaInstituto de Neurociencias, Hospital Cruz Roja, P.º de la Victoria, Córdoba, 14004, España.
Laura Muñoz-MillánDepartamento de Ingeniería Electrónica y de Computadores, Universidad de Córdoba, Edificio Leonardo Da Vinci, Campus de Rabanales, Córdoba, 14071, España.
David Cáceres-GómezDepartamento de Ciencia de la Computación e Inteligencia Artificial, Universidad de Córdoba, Edificio Marie Curie, Campus de Rabanales, Córdoba, 14071, España.
Rafael López-LuqueInstituto de Neurociencias, Hospital Cruz Roja, P.º de la Victoria, Córdoba, 14004, España.
Eduardo Cañete-CarmonaDepartamento de Ingeniería Electrónica y de Computadores, Universidad de Córdoba, Edificio Leonardo Da Vinci, Campus de Rabanales, Córdoba, 14071, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gamification in stroke rehabilitation is a method that applies game-design elements to enhance patient engagement, motivation, and functional recovery. This study reviews 68 gamified prototypes for post-stroke neurorehabilitation published between 2019 and 2023, integrating hardware, software, and gamification design criteria under a unified framework. Technological trends, therapeutic domains, and gamification components are analyzed, yielding eight overarching guidelines for developing patient-centered devices. Results confirm a predominance of solutions targeting the functional domain (79% motor), an expansion of immersive environments (VR/IVR, 66%), and the emergence of hybrid systems that combine robotics, sensors, and artificial intelligence algorithms to adapt assistance in real time. However, affective and social domains remain underrepresented, and clinical interoperability continues to pose challenges. Based on current design criteria, future directions propose advanced gamification frameworks that foster intrinsic motivation. By laying the groundwork for more motivating, personalized, and cost-effective gamified therapies, this work offers a practical guide for engineers, therapists, and developers.

Indexed as

SoftwareSoftware DesignStroke RehabilitationVideo GamesHumansRoboticsStrokeDesign considerationsGamificationGamified designHardwareSoftwareStroke

Identifiers

PMID41774339
PMCPMC13121546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.