Evidence map›Paper›PMID 41774284›Full record

ArticleInternational ophthalmology2026

Surgically induced necrotizing scleritis after orbital surgery with intraconal tumor excision: a case report.

Sylves Patrick, Jasmine Rashid, Shee Wen Chua, Amalina Juares Rizal, Hanida Hanafi

Abstract readCase Reports
In one paragraph

Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sylves PatrickDepartment of Ophthalmology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah (UMS), 88400, Kota Kinabalu, Sabah, Malaysia. sylves@ums.edu.my.
Jasmine RashidOculoplastic and Reconstructive Unit, Department of Ophthalmology, Queen Elizabeth Hospital, 88586, Kota Kinabalu, Sabah, Malaysia.
Shee Wen ChuaDepartment of Ophthalmology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah (UMS), 88400, Kota Kinabalu, Sabah, Malaysia.
Amalina Juares RizalOculoplastic and Reconstructive Unit, Department of Ophthalmology, Queen Elizabeth Hospital, 88586, Kota Kinabalu, Sabah, Malaysia.
Hanida HanafiOculoplastic and Reconstructive Unit, Department of Ophthalmology, Queen Elizabeth Hospital, 88586, Kota Kinabalu, Sabah, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgically induced necrotizing scleritis (SINS) is a blinding ocular disease characterized byinfl ammation with scleral necrosis. It occurs as early as one day after ocular surgery, although it can also occur years later. Commonly, it occurs after pterygium and cataract surgeries CASE PRESENTATION: Here, we report a case of a 40-year-old woman with underlying diabetes mellitus whounderwent a successful excisional biopsy via a swinging upper eyelid approach with lateral canthotomy andcantholysis, along with disinsertion of the superior and lateral rectus muscles, for an orbital cavernous venousmalformation. However, 9 weeks postoperatively, the patient developed persistent pain in the right eye (RE),especially with lateral gaze, which was not relieved with oral ibuprofen. At 16 weeks postoperative, an RE focal areaof scleral necrosis with surrounding conjunctival injection was noted at the superotemporal bulbar region. Magneticresonance imaging of the orbit and brain revealed RE focal thickening at the posterolateral sclera, posterior to thelateral rectus muscle insertion, suggesting posterior scleritis. The patient was treated with oral prednisolone (40mg/day) followed by a tapering regimen with adjunctive methotrexate (20 mg/week). After three months of oralprednisolone and six months of methotrexate, her disease resolved with no complications.

conclusionSINS is a rare but potentially sight-threatening complication following orbital surgery with intraconaltumor excision. Persistent pain can be a useful clue before the clinical signs become apparent.

Indexed as

Ophthalmologic Surgical ProceduresOrbitOrbital NeoplasmsPostoperative ComplicationsScleraScleritisAdultFemaleHumansMagnetic Resonance ImagingNecrosisNecrotizing scleritisOrbital surgeryOrbitotomySINSSurgically induced necrotizing scleritis

Identifiers

PMID41774284
PMCPMC12956942

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