Evidence map›Paper›PMID 41774213›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Promoting intervertebral disc fusion using BMP2, L51P, and the EP4 agonist KMN-159: synergistic osteogenesis in human annulus fibrosus cells.

Shuimu Chen, Xinggui Tian, Stefan Zwingenberger, Christoph E Albers, Benjamin Gantenbein, Sonja Häckel

Abstract read
PubMed Publisher
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuimu ChenDepartment of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland.ORCID http://orcid.org/0009-0003-1820-380X
Xinggui TianCenter for Orthopaedic, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, 17475, Greifswald, Germany.ORCID http://orcid.org/0000-0003-3619-3943
Stefan ZwingenbergerCenter for Orthopaedic, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, 17475, Greifswald, Germany.ORCID http://orcid.org/0000-0002-1831-3035
Christoph E AlbersDepartment of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland.ORCID http://orcid.org/0000-0003-2751-3458
Benjamin GantenbeinDepartment of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland. benjamin.gantenbein@unibe.ch.ORCID http://orcid.org/0000-0002-9005-0655
Sonja HäckelDepartment of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland. sonja.haeckel@insel.ch.ORCID http://orcid.org/0000-0002-9415-6633

Funding

China Scholarship Council #202208170027Deutsche Wirbelsäulenstiftung NASchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung CSRK3_237950
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Annulus fibrosus cellsBMP2KMN159L51POsteogenesisSpinal fusion

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.