Evidence map›Paper›PMID 41773712›Full record

SynthesisThe American journal on addictions2026

Addressing tobacco use in the context of opioid use disorder: A systematic review of smoking cessation interventions.

Suprit Parida, Victoria Ameral, Noah Wolkowicz, Megan M Kelly, Jessica A Patterson, Mehmet Sofuoglu, R Ross MacLean

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in The American journal on addictions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suprit ParidaDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Victoria AmeralMental Illness Research, Education, and Clinical Center, VA Bedford Healthcare System, Bedford, Massachusetts, USA.
Noah WolkowiczDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
Megan M KellyMental Illness Research, Education, and Clinical Center, VA Bedford Healthcare System, Bedford, Massachusetts, USA.
Jessica A PattersoneVISN 1 Knowledge Library, VA Connecticut Healthcare System, West Haven, Connecticut, USA.
Mehmet SofuogluDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
R Ross MacLeanDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.

Funding

CSRD VA IK2 CX002286U.S. Department of Veterans Affairs 1IK2CX002286
6 · The paper itself

Abstract

BACKGROUND AND

objectivesRates of tobacco use disorder (TUD) are high among individuals with opioid use disorder (OUD), who consistently show lower response rates to evidence-based treatment approaches for TUD relative to the general population. This systematic review aims to provide a comprehensive and updated examination of the current evidence regarding TUD treatments for individuals with OUD. We first summarize potential mechanisms driving TUD and treatment nonresponse among those with OUD, given the likely roles of overlapping reward and withdrawal processes in co-occurrence and treatment challenges. We then provide an updated review of the relevant literature on treating TUD among those with OUD.

methodsOur review identified a total of 25 studies, with 9 examining pharmacological treatments, 5 examining behavioral treatments, and 11 examining a combination treatment approach.

resultsConsistent with previous research, pharmacological treatments were generally ineffective for smoking cessation among those with OUD. No studies reported continuous abstinence at 6 months post-quit date. Contingency management interventions showed some promise but smoking largely resumed after incentives were removed. DISCUSSION AND

conclusionsOverall, findings demonstrate limited progress in identifying durable, effective smoking cessation interventions for individuals with OUD. SCIENTIFIC SIGNIFICANCE: Traditional cessation treatment approaches fail to address smoking in individuals with OUD. Novel pharmacological and behavioral strategies that can be implemented into existing medications for OUD clinical care are necessary.

Indexed as

Opioid-Related DisordersSmoking CessationTobacco Use DisorderBehavior TherapyHumans

Identifiers

PMID41773712
PMCPMC13485321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.