Evidence map›Paper›PMID 41773558›Full record

Observational studyJMIR research protocols2026

The National Dental Practice-Based Research Network Dental Implant Restoration Registry to Evaluate Dental Implant Outcomes in Community Practice Settings: Protocol for a Prospective Observational Study.

Joana Cunha-Cruz, Danyelle Barton, David Cochran, Phillip Crawford, Farahnaz Fahimipour, Ellen Funkhouser, Nicolaas C Geurs, Gregg H Gilbert, James D Johnson, Ning Smith and 5 more

Abstract readObservational Study
In one paragraph

Observational study in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joana Cunha-CruzDepartment of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, 1717 11th Avenue S, Suite 402E, Birmingham, AL, United States, 1 205-996-5298.ORCID 0000-0002-8276-9838
Danyelle BartonKaiser Permanente, Portland, OR, United States.ORCID 0009-0004-3062-5754
David CochranDepartment of Periodontology, University of Texas Health San Antonio, San Antonio, TX, United States.ORCID 0009-0009-4994-7733
Phillip CrawfordKaiser Permanente, Portland, OR, United States.ORCID 0000-0003-0774-7898
Farahnaz FahimipourDepartment of Periodontology, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0002-3494-817X
Ellen FunkhouserDepartment of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, 1717 11th Avenue S, Suite 402E, Birmingham, AL, United States, 1 205-996-5298.ORCID 0000-0002-9689-6491
Nicolaas C GeursDepartment of Periodontology, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0001-5713-7241
Gregg H GilbertDepartment of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, 1717 11th Avenue S, Suite 402E, Birmingham, AL, United States, 1 205-996-5298.ORCID 0000-0003-2017-625X
James D JohnsonCollege of Dentistry, University of Florida, Gainesville, FL, United States.ORCID 0009-0005-9150-4830
Ning SmithKaiser Permanente, Portland, OR, United States.ORCID 0000-0002-0149-6568
Kaur ManinderDepartment of Periodontology, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0000-0001-5636-4530
Sarah Jane StartleyDepartment of Periodontology, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL, United States.ORCID 0009-0009-9315-8846
Kimberly StewartKaiser Permanente, Portland, OR, United States.ORCID 0009-0009-2508-2560
Lisa WaiwaioleKaiser Permanente, Portland, OR, United States.ORCID 0000-0002-4280-220X
National Dental PBRN Collaborative GroupSee Acknowledgments.

Funding

The National Dental PBRN - Administrative CoreU19DE028717 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2019 to 2025
$23.5M
NDPBRN Opioid SurveyU01DE028727 · NIDCR · KAISER FOUNDATION RESEARCH INSTITUTE · PI CARMIT Kurn MCMULLEN · 2019 to 2026
$16.0M
A Dental implant registry of treatment outcomes of implant therapy by practitioners in the National Dental Practice Based Research NetworkUH3DE030090 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Joana Cunha-Cruz · 2022 to 2026
$2.1M
NIDCR NIH HHS U01 DE028727NIDCR NIH HHS U19 DE028717NIDCR NIH HHS UH3 DE030090
6 · The paper itself

Abstract

Background: Dental implants are a widely used therapeutic option for tooth replacement; however, biological and prosthetic complications may compromise implant success. While prior research has largely focused on academic or specialty settings, data on implant outcomes in community dental practices remain limited. Objective: This study aims to establish a national registry within the National Dental Practice-Based Research Network to evaluate the incidence of and factors associated with biological and prosthetic complications following implant therapy in community practice settings. Methods: This prospective observational cohort study plans to include approximately 2000 implant restorations from 1550 patients receiving implant restorations from 150 practitioners across 6 regional network nodes. Clinical, implant, and prosthetic characteristics will be recorded at baseline, with annual follow-up visits collecting data on complications, implant failures, prosthetic issues, and patient-reported outcomes. Digitized radiographs will be centrally reviewed for peri-implant bone changes, emergence angle, and prosthetic fit. The primary outcome is the incidence of biological and prosthetic complications. Secondary analyses will evaluate patient-centered outcomes and identify risk factors for complications. Multilevel mixed-effects regression and time-to-event analyses will be used to account for clustering and censored data. Results: Of 430 practitioners who expressed initial interest, 187 (43.5%) completed training and began patient enrollment, with 143 (76.5%) of these practitioners enrolling at least one participant. A total of 1453 patients were registered between August 2022 and October 2024. Practitioner activity and enrollment peaked in late 2023. Overall, 1178 (81.1%) baseline patient surveys and 1453 (100%) baseline clinical forms were completed, covering 2087 dental implant restorations. Conclusions: The registry will generate robust, real-world evidence on implant-related complications and their predictors in community practice. The findings will enhance clinical decision-making; support personalized risk assessment; and, ultimately, improve patient outcomes in implant dentistry.

Indexed as

Dental ImplantsRegistriesFemaleHumansObservational Studies as TopicProspective StudiesResearch DesignDental Implantsdental implantsdental prosthesisdentures, implant supportedoral healthpractice-based researchprospective studies

Identifiers

PMID41773558
PMCPMC12954579

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.