Evidence map›Paper›PMID 41773529›Full record

ArticleThe Journal of international medical research2026

Acute ischemic stroke incidence after influenza or coronavirus disease 2019 among older US adults: A cross-sectional study using electronic health records.

Emilia H Koumans, Julia Raykin, Fátima Coronado, Sharon Saydah, Tegan K Boehmer, Jennifer Wiltz, Shikha Garg, Carol E Desantis, Thomas W Carton, Lindsay G Cowell and 9 more

Abstract read
In one paragraph

Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Emilia H KoumansCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, United States.ORCID 0000-0001-7184-2107
Julia RaykinOffice of Public Health Data, Surveillance and Technology, Centers for Disease Control and Prevention, United States.
Fátima CoronadoDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, United States.
Sharon SaydahCoronavirus and Other Respiratory Viruses Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, United States.
Tegan K BoehmerOffice of Public Health Data, Surveillance and Technology, Centers for Disease Control and Prevention, United States.
Jennifer WiltzNational Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, United States.
Shikha GargInfluenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, United States.
Carol E DesantisOffice of Public Health Data, Surveillance and Technology, Centers for Disease Control and Prevention, United States.
Thomas W CartonLouisiana Public Health Institute, United States.
Lindsay G CowellPeter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, United States.
Deepika ThackerNemours Children's Health, United States.
Jonathan ArnoldDepartment of Medicine, University of Pittsburgh School of Medicine, United States.
Sonja A RasmussenJohns Hopkins University School of Medicine; United States.
Samantha J SmithHarvard Pilgrim Health Care Institute, Harvard Medical School, United States.
Kimberly BarrettHarvard Pilgrim Health Care Institute, Harvard Medical School, United States.
Christine DraperHarvard Pilgrim Health Care Institute, Harvard Medical School, United States.
Elizabeth A LundeenDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, United States.
Rebecca C WoodruffDivision for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, United States.
Jason P BlockHarvard Pilgrim Health Care Institute, Harvard Medical School, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAlthough coronavirus disease 2019 and influenza are recognized risk factors for thrombotic conditions, the incidence of acute ischemic stroke following these infections since 2022 remains unknown.MethodsPatients aged ≥65 years with no prior history of stroke, coronavirus disease 2019, or influenza who developed acute ischemic stroke from 3 days before to 28 days after a coronavirus disease 2019 or influenza diagnosis were identified using PCORnet and HealthVerity data collected from 1 January to 31 December 2022. Demographic characteristics, underlying conditions, level of care, outcomes, and acute ischemic stroke incidence were described and compared between patients with early acute ischemic stroke occurring from -3 to 7 days from the diagnosis date and late acute ischemic stroke occurring from 8 to 28 days.ResultsAmong 245,352 patients in PCORnet and 639,396 patients in HealthVerity aged ≥65 years with COVID-19, the incidence of early acute ischemic stroke following coronavirus disease 2019 (PCORnet: 962 per 100,000; HealthVerity: 447 per 100,000) and influenza (PCORnet: 589 per 100,000; HealthVerity: 387 per 100,000) was significantly higher than that of late acute ischemic stroke (coronavirus disease 2019 PCORnet: 81 per 100,000; HealthVerity: 141 per 100,000; influenza PCORnet: 75 per 100,000; HealthVerity: 15 per 100,000) (all

Indexed as

COVID-19Influenza, HumanIschemic StrokeAgedAged, 80 and overCross-Sectional StudiesElectronic Health RecordsFemaleHumansIncidenceMaleRisk FactorsSARS-CoV-2United Statescomplicationscoronavirus disease 2019Ischemic strokeolder adults

Identifiers

PMID41773529
PMCPMC12957579

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.