Evidence map›Paper›PMID 41773222›Full record

ArticleInternational journal of women's health2026

Hysteroscopic Cold Knife Separation Combined with Autologous Platelet Rich Plasma for the Treatment of Intrauterine Adhesions: A Comparative Study.

Haiyan Li, Yajun Rong, Yanan Li, Xiaojing Wang

Abstract read
In one paragraph

Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Haiyan LiDepartment of Gynecology, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, 050011, People's Republic of China.
Yajun RongDepartment of Gastrointestinal Surgery, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, 050011, People's Republic of China.
Yanan LiDepartment of Traditional Chinese Medicine, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, 050011, People's Republic of China.
Xiaojing WangDepartment of Traditional Chinese Medicine, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, 050011, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the preliminary effect of hysteroscopic cold knife separation combined with autologous platelet rich plasma (PRP) in the treatment of intrauterine adhesions (IUA) and prevention of postoperative re-adhesions. Methods: Retrospectively, 110 patients with IUA treated in our hospital during January 2022 to January 2024 were selected for the study, and divided into 58 cases in the cold knife + PRP group and 52 cases in the cold knife group. Clinical outcomes, surgical parameters, sex hormone levels [estradiol (E2), luteinizing hormone (LH), follicle-stimulating hormone (FSH)], inflammatory markers [C-reactive protein (CRP), matrix metalloproteinase-9 (MMP-9), interleukin-8 (IL-8), interleukin-6 (IL-6)], and postoperative re-adhesion rates were compared between two groups. Results: The cold knife + PRP group had much higher total efficacy rate of 91.88% than 75.00% in the Cold Knife group ( Conclusion: In this preliminary study, hysteroscopic cold knife dissection combined with PRP showed a trend toward regulating sex hormone levels, mitigating inflammatory responses, and reducing re-adhesion incidence in IUA patients, suggesting its potential as a therapeutic option. However, larger-scale studies are needed to confirm these findings.

Indexed as

hysteroscopic cold knife dissectionplatelet-rich plasmapreventionuterine adhesion

Identifiers

PMID41773222
PMCPMC12950169

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.