Evidence map›Paper›PMID 41773218›Full record

ArticleHealth science reports2026

Neutrophil Gelatinase-Associated Lipocalin and Neutrophil-to-Lymphocyte Ratio as Indicators of Nephropathy in Type 2 Diabetic Mellitus Patients in Ghana: A Case-Control Study.

Allwell Adofo Ayirebi, Wina Ivy Ofori Boadu, Stephen Twumasi, Samuel Kwarteng, Benedict Sackey, Lilian Antwi Boateng, Joseph Boachie, Samuel Essien-Baidoo, Daniel Nii Martey Antonio, John Agyemang Sah and 9 more

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Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

19 authors.

Allwell Adofo AyirebiDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0009-0005-0805-9829
Wina Ivy Ofori BoaduDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0002-2660-1707
Stephen TwumasiDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0009-0002-8199-5806
Samuel KwartengDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0001-6114-2983
Benedict SackeyDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0003-1016-7720
Lilian Antwi BoatengDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0001-5635-7939
Joseph BoachieDepartment of Medical Laboratory Science University of Cape Coast Cape Coast Ghana.ORCID https://orcid.org/0000-0003-3950-6423
Samuel Essien-BaidooUniversity of Health and Allied Sciences Ho Ghana.ORCID https://orcid.org/0000-0002-8618-6648
Daniel Nii Martey AntonioDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0002-8953-5700
John Agyemang SahDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0003-0607-8581
Afua MarfowaaDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Mayfair Adwapa MpianiDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Joachim Baba DomosieDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Abiba KhalifahDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0009-0006-2846-4140
Emmanuel Ekow KorsahDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0009-0009-8695-6639
Ebenezer SenuDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0002-2973-8952
Eugene Arele AnsahDepartment of Molecular Medicine, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0009-0002-9845-3114
Joseph YorkeDepartment of Surgery, School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0002-5229-0340
Enoch Odame AntoDepartment of Medical Diagnostics, Faculty of Allied Health Sciences, College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.ORCID https://orcid.org/0000-0001-9023-6612

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Serum neutrophil gelatinase-associated lipocalin (sNGAL), a renal tubular marker, and neutrophil-to-lymphocyte ratio (NLR), a hematological inflammatory marker are two biomarkers that have recently received attention, because of their association with kidney disease. This study examined the diagnostic value sNGAL and NLR in type 2 diabetes mellitus (T2DM) patients with nephropathy. Materials and Methods: In this hospital-based case-control research, 97 T2DM participants and 70 healthy subjects were included. Participants' information was documented using a structured questionnaire and patient case records. Venous blood was drawn from each participant and early morning midstream urine samples were collected for blood and urine measurements respectively. Results: The prevalence of nephropathy among type 2 diabetics was 20.6%. sNGAL had a good performance (AUC = 0.793, Conclusions: Whiles sNGAL showed superiority and is recommended, NLR showed no significant group difference and poor, non-significant discrimination, indicating it is not a reliable standalone marker of diabetic nephropathy in this study.

Indexed as

diabetic nephropathymicroalbuminurianeutrophil‐to‐lymphocyte ratioserum neutrophil gelatinase‐associated lipocalintype 2 diabetes mellitus

Identifiers

PMID41773218
PMCPMC12949827

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