Evidence map›Paper›PMID 41773198›Full record

Articlenpj women's health2026

Menopausal hormone therapy and risk of neuropsychiatric disease: a drug target Mendelian randomisation study.

Louise S Schindler, Dipender Gill, Hannah Oppenheimer, Claudia Barth, Ole A Andreassen, Bogdan Draganski, Lars T Westlye, Anya Topiwala, Ann-Marie G de Lange

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in npj women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Louise S SchindlerSocial, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Dipender GillDept. of Epidemiology and Biostatistics, Imperial College London, London, UK.
Hannah OppenheimerDept. of Psychology, University of Oslo, Oslo, Norway.
Claudia BarthDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Ole A AndreassenCentre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Bogdan DraganskiNeurology Dept. and University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University Hospital Bern, University of Bern, Bern, Switzerland.
Lars T WestlyeDept. of Psychology, University of Oslo, Oslo, Norway.
Anya Topiwala *Nuffield Dept. of Population Health, Big Data Institute, University of Oxford, Oxford, UK.
Ann-Marie G de Lange *Dept. of Psychiatry, University of Oxford, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on whether menopausal hormone therapy (MHT) affects neurological or psychiatric disease is conflicting. As MHT acts by binding to oestrogen receptors (ER

Indexed as

Hormonal therapiesReproductive biology

Identifiers

PMID41773198
PMCPMC12949953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.