Evidence map›Paper›PMID 41773089›Full record

ArticleJFMS open reports

Pulmonary epithelial-myoepithelial carcinoma with high-grade transformation in a cat.

Tomokazu Nagashima, Tomohiro Oyamada, Aoba Takahashi, Yukino Machida, Hisashi Yoshimura, Yuuki Shichi, Kazuhiko Ochiai, Honoka Kawamura, Daigo Azakami, Masaki Michishita

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JFMS open reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomokazu NagashimaDepartment of Veterinary Pathology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Tomohiro OyamadaAnimal Medical Center, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Aoba TakahashiDepartment of Veterinary Pathology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Yukino MachidaDepartment of Veterinary Pathology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Hisashi YoshimuraLaboratory of Physiological Pathology, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Yuuki ShichiDivision of Aging and Carcinogenesis, Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Itabash, Tokyo, Japan.
Kazuhiko OchiaiLaboratory of Veterinary Hygiene, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Honoka KawamuraDepartment of Veterinary Pathology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.
Daigo AzakamiLaboratory of Clinical Oncology, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Masaki MichishitaDepartment of Veterinary Pathology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0353-3668

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Case summary: A 14-year-old spayed female Scottish Fold cat was presented to a private veterinary clinic for a health check. Radiography revealed a nodule measuring 1.0 cm diameter in the cranial segment of the cranial lobe of the left lung. On day 12, non-contrast-enhanced CT revealed a well-defined pulmonary nodule measuring 1.7 cm in diameter in the same area. On day 48, the nodule in the cranial segment of the left cranial lobe was resected by lobectomy. The nodule was firm and pale pink in surface colour. Microscopically, the mass was adjacent to the bronchi and bronchial glands and was composed of luminal cells forming the duct structure and an outer layer of non-luminal cells with squamoid differentiation. Tumour cells partially invaded into the surrounding parenchyma. Immunohistochemically, the luminal cells were positive for cytokeratin (CK) AE1/AE3, CK7, CK19, thyroid transcription factor-1 and human epidermal growth factor 2. Non-luminal cells were positive for CK AE1/AE3, p63, calponin, smooth muscle actin and p40. The Ki-67 indices of the luminal and non-luminal cells were 10.4% and 12.8%, respectively. Based on these findings, the tumour was diagnosed as a pulmonary epithelial-myoepithelial carcinoma with high-grade transformation as defined in the human World Health Organization classification. Relevance and novel information: This is the first report of pulmonary epithelial-myoepithelial carcinoma with high-grade transformation characterised by morphology and immunohistochemistry.

Indexed as

Epithelial-myoepithelial carcinomahigh-grade transformationimmunohistochemistrylung tumour

Identifiers

PMID41773089
PMCPMC12949761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.