ArticleJournal of occupational and environmental medicine2026
Exposure to Industrial Air Toxics and Risk of Breast Cancer in California: The Multiethnic Cohort Study.
Article in Journal of occupational and environmental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
objectiveEstimate breast cancer risk associated with residential industrial air pollutant exposure.
methodsWe analyzed 53,313 women in the California Multiethnic Cohort (1993-1996) for associations between 15 industrial pollutants and breast cancer incidence. Using Environmental Protection Agency Toxic Release Inventory data, sites were linked to geocoded residential histories via quadratic decay models to estimate 5-year lagged exposures. Cox models calculated risk per interquartile range increase, stratified by race/ethnicity and hormone receptor status.
resultsIncreased risk was associated with dichloromethane (hazard ratio [HR] = 1.17, 95% confidence interval [CI]: 1.05-1.29), tetrachloroethylene (HR = 1.53, CI: 1.39-1.69), 1,1,1-trichloroethane (HR = 1.77, CI: 1.65-1.91), diethanolamine (HR = 1.06, CI: 0.98-1.15), lead (HR = 1.02, CI: 1.00-1.03), and methyl ethyl ketone (HR = 1.27, CI: 1.15-1.41). Formaldehyde was associated only with hormone receptor-negative tumors (HR = 1.44, CI: 1.15-1.73).
conclusionsResidential exposure to certain industrial pollutants may increase breast cancer risk.
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