ArticleChild and adolescent psychiatry and mental health2026
Intergenerational transmission of maternal and adolescent depressive symptoms: cross-sectional and cross-lagged panel network analysis.
Article in Child and adolescent psychiatry and mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundMaternal depressive symptoms are a well-documented risk factor for adolescent depression, yet the symptom-level mechanisms of intergenerational transmission remain insufficiently understood.
methodsA total of 1140 mother-adolescent dyads completed the PHQ-9 at baseline (T1), with 921 dyads reassessed 6 months later (T2). Cross-lagged panel network analysis was applied to examine symptom-level stability, cross-symptom predictions, and intergenerational associations across time.
resultsThe analysis revealed strong autoregressive effects for maternal sleep disturbance and adolescent suicidal ideation, indicating that these symptoms were particularly persistent over time. Within-group cross-symptom effects were also observed: adolescent suicidal ideation predicted later sad mood, anhedonia, and sleep problems, while maternal fatigue and guilt predicted subsequent anhedonia and appetite problems, and maternal psychomotor changes predicted later suicidal ideation. Intergenerational pathways were identified whereby maternal psychomotor symptoms at T1 predicted adolescent psychomotor symptoms at T2 (β = 0.11), and maternal depressed mood predicted adolescent sleep problems (β = 0.10), with a reverse pathway from adolescent guilt to maternal guilt (β = 0.08).
conclusionsDepressive symptoms in mothers and adolescents are maintained through temporally stable and cross-activating symptoms within individuals, and transmitted across generations through specific symptom-to-symptom pathways. These findings refine theoretical understanding of how depressive symptoms persists and spreads in families and highlight key symptoms as promising targets for future research and preventive efforts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.