Evidence map›Paper›PMID 41772636›Full record

ArticleJournal of cardiothoracic surgery2026

Cardiac ochronosis with severe aortic and mitral valve stenosis: a challenge case.

Mukan Kağan Kuş, Burak Bozkurt, Talib Durak, İsmail Yücesin Arslan, Mehmet Kaplan

Abstract readCase Reports
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mukan Kağan KuşDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Barbaros Mah. Sedef Sk. Onur Sitesi No:3c Köknar Apt D:4,Üsküdar, Istanbul, 34674, Turkey. mukankagankus@gmail.com.ORCID http://orcid.org/0000-0002-4102-1110
Burak BozkurtDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Barbaros Mah. Sedef Sk. Onur Sitesi No:3c Köknar Apt D:4,Üsküdar, Istanbul, 34674, Turkey.ORCID http://orcid.org/0000-0001-7602-8120
Talib DurakDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Barbaros Mah. Sedef Sk. Onur Sitesi No:3c Köknar Apt D:4,Üsküdar, Istanbul, 34674, Turkey.ORCID http://orcid.org/0009-0006-0278-4939
İsmail Yücesin ArslanDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Barbaros Mah. Sedef Sk. Onur Sitesi No:3c Köknar Apt D:4,Üsküdar, Istanbul, 34674, Turkey.ORCID http://orcid.org/0000-0001-9313-2165
Mehmet KaplanDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Barbaros Mah. Sedef Sk. Onur Sitesi No:3c Köknar Apt D:4,Üsküdar, Istanbul, 34674, Turkey.ORCID http://orcid.org/0000-0003-2041-8335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ochronosis is a hereditary disorder characterized by black pigmentation in tissues. Cardiac ochronosis is most commonly associated with aortic stenosis, while mitral stenosis is a less frequently observed involvement. In this case presentation, we will discuss ochronosis diagnosed during open heart surgery in a patient who had not been previously diagnosed. Our patient underwent surgery for aortic valve and mitral valve replacement. The aortic root, mitral valve, and aortic-mitral curtain were found to be calcified, and a mandatory Commando procedure was performed. The coronary buttons could not be mobilized, and the Cabrol procedure was applied. In cases of ochronosis, it is a fact that decalcification can lead to significant complications, and the involvement of the aortic-mitral curtain must also be considered by the surgeon.

Indexed as

Aortic Valve StenosisMitral Valve StenosisOchronosisHeart Valve Prosthesis ImplantationHumansMale

Identifiers

PMID41772636
PMCPMC13059246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.