Evidence map›Paper›PMID 41772534›Full record

Trial reportBMC medical education2026

Augmedicine: Ultrasound: Training in ultrasound using XR - a randomized controlled trial.

Tessa A Mulder, Robin C Jacobs, Manon S Zuurmond, Adel Qaddoumi, Madelien V Regeer, Friedo W Dekker, Martijn P Bauer, Alexandr Srámek, Alexandra M J Langers, Beerend P Hierck

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tessa A MulderDepartment of Internal Medicine, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands. t.a.mulder@lumc.nl.
Robin C JacobsDepartment of Internal Medicine, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Manon S ZuurmondDepartment of Internal Medicine, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Adel QaddoumiLeiden Learning and Innovation Centre, Leiden University, The Hague, The Netherlands.
Madelien V RegeerDepartment of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands.
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands.
Martijn P BauerDepartment of Internal Medicine, Leiden University Medical Centre, Albinusdreef 2, Leiden, 2333 ZA, The Netherlands.
Alexandr SrámekDepartment of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
Alexandra M J Langers *Centre for Innovation in Medical Education, Leiden University Medical Centre, Leiden, The Netherlands.
Beerend P Hierck *Department of Clinical Sciences-Anatomy and Physiology, Veterinary Medicine Faculty, Utrecht University, Utrecht, The Netherlands.

Funding

Leiden University Fund / Prof. A.A.H. Kassenaar Fonds LUF23025-2-SKF
6 · The paper itself

Abstract

backgroundPoint-of-care ultrasound (POCUS) is a diagnostic tool increasingly used. For novices, challenges such as probe orientation and hand-eye coordination make POCUS difficult to master. Extended reality (XR) can enhance POCUS training by projecting 3D anatomical models and offering real-time feedback on probe positioning. We developed the ‘Augmedicine: Ultrasound’ XR application, which enables heart POCUS training without the need for an instructor or test subject. The goal of this study was to determine whether XR-based training is non-inferior to standard POCUS training.

methodsMedical students in their internal medicine clerkship were randomized to XR-integrated POCUS training or standard training under direct instructor supervision. Competence was assessed through a practical test, where students obtained two ultrasound images and measured e-point septal separation (EPSS) and tricuspid annular plane systolic excursion (TAPSE). Expert-determined values served as references and were used to determine non-inferiority. Secondary endpoints included test completion time and image quality.

resultsFifty-six students participated: 28 in the XR group and 28 in the standard training group. The mean difference in EPSS between groups was 0.3 mm (95% CI − 0.8 to 1.3 mm), and for TAPSE 0.5 mm (95% CI − 1.4 to 2.6 mm). In both cases, the confidence intervals remained within the predefined non-inferiority margins, indicating comparable performance between XR-based and standard training. There was no significant difference in the time taken to complete the test, and image quality was slightly higher in the XR group compared to the standard group.

conclusionXR-based POCUS training proved to be non-inferior to standard training in acquiring and measuring basic cardiac ultrasound images. Beyond comparable performance, the XR approach offers clear benefits in flexibility, scalability, and reduced reliance on instructors and test subjects—making it particularly valuable for training large cohorts and allowing learners to practice at any time and for any duration. These findings support the integration of XR as a practical and effective addition to ultrasound education.

trial registrationISRCTN Registry, ISRCTN13887304. https://doi.org/10.1186/ISRCTN13887304

Indexed as

Clinical CompetenceEchocardiographyInternal MedicinePoint-of-Care SystemsVirtual RealityClinical ClerkshipFemaleHumansMaleStudents, MedicalUltrasonographyEchocardiographyExtended realityHeartPOCUSPoint-of-care ultrasoundThree-dimensional anatomyTraining

Identifiers

PMID41772534
PMCPMC13188371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.