Evidence map›Paper›PMID 41772523›Full record

ArticleBMC musculoskeletal disorders2026

Psychosocial correlates of central sensitization and kinesiophobia: the role of Type D personality in fibromyalgia - a cross-sectional study.

Hatice Betigul Meral, Tehran Aliyeva, Zeynep Meral Obholzer, Erkan Kolak

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hatice Betigul MeralDepartment of Physical Medicine and Rehabilitation, Istanbul Medipol University, Istanbul, Türkiye. meralbetigul@gmail.com.ORCID http://orcid.org/0000-0002-7519-8184
Tehran AliyevaDepartment of Neurology, Istanbul Medipol University, Istanbul, Türkiye.ORCID http://orcid.org/0000-0001-9756-941X
Zeynep Meral ObholzerDepartment of Psychiatry, Oxford Health NHS Foundation Trust, Oxford, United Kingdom.ORCID http://orcid.org/0000-0002-1381-480X
Erkan KolakDepartment of Physical Medicine and Rehabilitation, Basaksehir Cam and Sakura City Hospital, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-7479-5323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibromyalgia (FM) is a multifactorial syndrome involving central sensitization and psychosocial factors such as fear of movement and emotional distress. Type D personality (TDP) may exacerbate these factors, but its role in FM remains unclear. This study aimed to investigate the associations between TDP and central sensitization, kinesiophobia, disease severity, and psychological distress in patients with FM.

methodsA total of 120 women (60 with FM, 60 healthy controls) aged 18–60 years were included in this cross-sectional study. Participants were assessed using the Type D Scale-14 (DS-14), Central Sensitization Inventory (CSI), Tampa Scale for Kinesiophobia (TSK), Fibromyalgia Impact Questionnaire (FIQ), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Visual Analog Scale (VAS), and Short Form-36 (SF-36). Multiple linear regression analyses with backward elimination based on the Akaike Information Criterion were conducted to identify independent predictors of CSI and FIQ scores.

resultsTDP was present in 61.7% of patients and 30% of controls (p < 0.001). Patients with TDP had significantly higher CSI scores (61 ± 9 vs. 34 ± 10, p < 0.001), TSK scores (42 ± 4 vs. 29 ± 6, p < 0.001), and FIQ scores (68.7 ± 11.1 vs. 45.9 ± 9.7, p < 0.001) compared to non-Type D patients. Pain intensity (VAS: 8 ± 1 vs. 6 ± 2, p = 0.004) and pain duration (104 ± 92 vs. 59 ± 53 months, p = 0.046) were significantly higher in patients with TDP. Furthermore, strong positive correlations were found between DS-14 subscale scores and clinical parameters in FM patients, including CSI (r = 0.84), TSK (r = 0.75), and FIQ (r = 0.76) (all p < 0.001). Among the DS-14 subscales, negative affectivity independently predicted both central sensitization symptoms (CSI; β = 0.27, p = 0.018) and disease severity (FIQ; β = 0.49, p = 0.004) in multivariable analyses.

conclusionsTDP is highly prevalent among patients with FM, and patients with Type D traits demonstrated higher central sensitization, greater fear of movement, more severe clinical symptoms, and lower quality of life compared to those without these traits. These findings underscore the importance of incorporating personality traits into routine clinical assessment and support the adoption of more individualized, psychologically informed treatment approaches.

Indexed as

Central Nervous System SensitizationFibromyalgiaKinesiophobiaType D PersonalityAdolescentAdultCross-Sectional StudiesFemaleHumansMiddle AgedPain MeasurementSeverity of Illness IndexYoung AdultChronic painFibromyalgiaKinesiophobiaPersonalityType D

Identifiers

PMID41772523
PMCPMC13067606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.